The UCLA South African Trauma Research Training Program

描述（由申请人提供）：加州大学洛杉矶分校/南非创伤培训研究（Phodiso）计划寻求额外五年的资金，以准备未来的调查人员在南非高水平的人际和社区暴力和故意伤害的背景下进行创伤暴露和伤害预防的研究。Phodiso计划是加州大学洛杉矶分校和南非研究联盟（SARC）之间的国际合作，该联盟包括人文科学研究理事会（HSRC），西北大学（NWU）和开普敦大学（UCT），并基于三个NIH资助的项目：1）Eban项目，一项随机临床试验，测试艾滋病毒血清不一致的非洲裔美国夫妇的文化一致性干预（R01;（2）南非妇女遭受强奸的后果（Fulufhelo项目），一项调查南非妇女遭受强奸后短期和长期心理社会后遗症的研究（R 03; 2009-2012）; 3）针对少数民族博士后学者和对研究艾滋病毒/艾滋病感兴趣的早期职业调查人员的艾滋病毒/艾滋病翻译培训方案，精神健康和药物滥用以及相关的共病差异（R25; 2009-2011年）。在生态和社会学习理论的指导下，Phodiso学者的研究重点将是尽量减少南非创伤暴露对健康和心理健康的负面影响，特别是抑郁症和创伤后应激障碍（PTSD）。在过去的五年里，我们的多学科培训计划提出扩大调查和培训的生物和遗传标记和压力介质，从而成为一个更全面的生物行为创伤培训计划。在最初供资期间，有8名学者接受了培训，他们现在将组成技术咨询小组。对于这次更新，加州大学洛杉矶分校和SARC核心教师和TAG将在全国范围内进行申请过程，每年选择一名早期职业研究候选人进行为期两年的博士后研究。学者将获得研究指导，包括四分之一的研究（即，为期3个月），每年在南非举行一次甄选和规划会议和一次短期创伤讲习班。学者们将在南非开展自己的研究项目，作为该领域未来研究的基础，并与他们的SARC主办大学和TAG导师密切合作。Phodiso创伤培训计划和学者的研究生涯将随着时间的推移进行跟踪。具体而言，培训计划的可持续性和融入学术，私人和政府支持的机构以及学者建立和维持独立研究事业的能力将被评估和记录。未来的目标将包括鼓励南非政府支持，认可和采用Phodiso计划作为跨文化创伤研究培训的成功和可复制的模式。 公共卫生相关性：加州大学洛杉矶分校/南非创伤培训研究（Phodiso）计划寻求额外五年的资金，以准备未来的调查人员在南非的人际和社区暴力和故意伤害的高水平的背景下进行创伤和伤害暴露的研究。作为加州大学洛杉矶分校和南非研究联盟（SARC）之间的国际合作，其中包括人文科学研究理事会（HSRC），西北大学（NWU）和开普敦大学（UCT），Phodiso的公共卫生使命是：1）增加训练有素的南非创伤研究人员的数量; 2）将研究结果转化为文化上一致的创伤和伤害预防和治疗方案; 3）促进社区能力和基础设施的建设，使南非人民受益。

DESCRIPTION (provided by applicant): The UCLA/South African Trauma Training Research (Phodiso) Program seeks five additional years of funding to prepare future investigators to conduct research on trauma exposure and injury prevention in the context of South Africa's high levels of interpersonal and community violence and intentional injuries. The Phodiso Program is an international collaboration between UCLA and the South African Research Consortium (SARC), which includes the Human Sciences Research Council (HSRC), North-West University (NWU), and University of Cape Town (UCT) and is based on three NIH-funded projects: 1) The Eban Project, a randomized clinical trial testing a culturally congruent intervention for HIV serodiscordant African American couples (R01; 2001-2011); 2) The Aftermath of Rape Among South African Women (The Fulufhelo Project), a study examining the short and long-term psychosocial sequelae of rape among South African women (R03; 2009-2012); and 3) The HIV/AIDS Translational Training Program (HATT) for racial and ethnic minority postdoctoral Scholars and early career investigators interested in studying HIV/AIDS, mental health and substance abuse and associated co-morbid disparities (R25; 2009-2011). Guided by ecological and social learning theories, the focus of the Phodiso Scholar's research will be to minimize the negative health and mental health effects of trauma exposure, specifically depression and post-traumatic stress disorder (PTSD), in South Africa. Developed over the past five years, our multidisciplinary training program proposes to expand to investigate and train on biologic and genetic markers and mediators of stress and thus, to be a more comprehensive biobehavioral trauma training program. During the initial funding period, eight scholars were trained and will now compose the Technical Advisory Group (TAG). For this renewal, the UCLA and SARC core faculty and TAG will conduct a countrywide application process to select one early career research candidates per year for a two-year postdoctoral fellowship. Scholars will receive research mentorship including a quarter of study (i.e., a 3-month period) at UCLA, one selection and planning meeting and one short-term trauma workshop each year in South Africa. Scholars will conduct their own research projects in South Africa as a basis for future studies in this field, as well as work closely with their SARC host university and TAG mentors. The Phodiso Trauma Training program and the research careers of the scholars will be tracked over time. Specifically, the sustainability of the training program and integration into academic, private, and government-supported agencies and the Scholar's ability to establish and sustain independent research careers will be evaluated and documented. Future goals will include encouraging the South African government to support, endorse and adopt the Phodiso program as a successful and replicable model of cross-cultural trauma research training. PUBLIC HEALTH RELEVANCE: The UCLA/South African Trauma Training Research (Phodiso) Program seeks five additional years of funding to prepare future investigators to conduct research on trauma and injury exposure in the context of South Africa's high levels of interpersonal and community violence and intentional injuries. As an international collaboration between UCLA and the South African Research Consortium (SARC), which includes the Human Sciences Research Council (HSRC), North-West University (NWU), and University of Cape Town (UCT), Phodiso's public health mission is to: 1) Increase the number of well-trained South African trauma researchers; 2) Translate research findings to culturally congruent trauma and injury prevention and treatment programs and; 3) Facilitate building of community capacity and infrastructure that benefit the people of South Africa.