Supplement to the Center for Culture, Trauma, and Mental Health Disparities

文化、创伤和心理健康差异中心的补充

• 批准号: 8137434
• 负责人: GAIL E. WYATT
• 金额: $ 18.39万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-08-11 至 2013-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8137434
• 关键词: Acute; Adult; African American; Biological; Child; Child Sexual Abuse; Childhood; Chronic; Chronic stress; Computer Assisted; Data; Data Analyses; Event; Funding; Future; Health; Health Status; Health Status Indicators; Individual; Intervention; Intervention Studies; Interview; Latino; Life Cycle Stages; Mental Depression; Mental Health; Modeling; Outcome; Personal Satisfaction; Physiological; Population; Post-Traumatic Stress Disorders; Poverty; Psychosocial Factor; Religion and Spirituality; Resources; Risk; Risk Estimate; Sampling; Sex Characteristics; Statistical Methods; System; Techniques; Testing; Time; Trauma; Woman; allostatic load; base; critical developmental period; ethnic difference; health disparity; high risk; indexing; laptop; men; predictive modeling; psychosocial; racial and ethnic; resilience; trauma centers

DESCRIPTION (provided by applicant): We are requesting supplemental funding to conduct secondary analyses of data collected and integrated from 5 studies nearing completion in the Collaborative Center for Trauma and Mental Health Disparities at UCLA (MH07345). Analyses will be based on comprehensive assessments of psychosocial factors relevant for mental health and related biological health risk indexes from 598 African American and Latino men and women. Using a sophisticated set of secondary data analytic techniques, we will describe mental health outcomes as they are predicted by a set of composite indexes of risks and resources over the life-course that may promote resilience and/or vulnerabilities in individuals at high risk. Domains include: (1) cumulative psychosocial burden of acute trauma and chronic psychosocial adversities in childhood and adulthood, (2) the cumulative burden of biological health risk indicators (BHRI) of allostatic load that are predicted to result from cumulative childhood and adulthood burdens of trauma and adversities, and (3) proposed protective resources (i.e. ethnic identify, religious well-being) that may moderate the relationships between cumulative psychosocial burden, cumulative BHRI burden and a composite mental health status index (i.e. depression/PTSD) in African Americans and Latinos. Analyses will be conducted on a sample of 598 adult African American and Latino men and women, including 228 African Americans (63 women, 165 men) and 370 Latinos (220 women, 150 men). Data were collected using laptops equipped with the Audio Computer-Assisted Self-Interview (ACASI) system augmented by private face to face interviews. Univariate and multivariate statistical methods will be used to develop predictor, moderator and mental health outcomes and to test a hypothesized predictive model of mental health status in this high-risk and understudied sample. This comprehensive, life-course approach offers a unique opportunity to identify multiple cumulative contributors to mental health disparities over time. PUBLIC HEALTH RELEVANCE: We expect that our results will inform the value of using composite indexes of risk and resilience in estimating risk for mental health outcomes, identify potential ethnic and gender differences in vulnerability and resilience factors in predicting these outcomes, and identify possible targets for future intervention research to reduce racial/ethnic mental health disparities.

描述（由申请人提供）：我们正在申请补充资金，对从加州大学洛杉矶分校创伤和心理健康差异合作中心（MH 07345）接近完成的5项研究中收集和整合的数据进行二次分析。分析将基于对598名非裔美国人和拉丁美洲男性和女性的心理健康相关心理社会因素和相关生物健康风险指数的综合评估。使用一套复杂的二级数据分析技术，我们将描述心理健康结果，因为它们是由一组风险和资源的综合指数预测的，这些指数可能会促进高风险个体的弹性和/或脆弱性。领域包括：（1）儿童期和成年期急性创伤和慢性心理社会逆境的累积心理社会负担，（2）预测由创伤和逆境的累积儿童期和成年期负担导致的非稳态负荷的生物健康风险指标（BHRI）的累积负担，以及（3）拟议的保护资源（即种族认同，宗教幸福感），这可能会缓和非裔美国人和拉丁美洲人的累积心理负担，累积BHRI负担和复合心理健康状况指数（即抑郁症/PTSD）之间的关系。将对598名成年非洲裔美国人和拉丁裔男性和女性的样本进行分析，其中包括228名非洲裔美国人（63名女性，165名男性）和370名拉丁裔（220名女性，150名男性）。数据收集使用笔记本电脑配备了音频计算机辅助自我采访（ACASI）系统的私人面对面采访增强。将使用单变量和多变量统计方法来开发预测因子、调节因子和心理健康结局，并在该高风险和研究不足的样本中检验心理健康状态的假设预测模型。这种全面的，生命过程的方法提供了一个独特的机会，以确定随着时间的推移心理健康差异的多个累积贡献者。 公共卫生关系：我们希望我们的研究结果将告知使用风险和弹性综合指数估计心理健康结果风险的价值，确定潜在的种族和性别差异的脆弱性和弹性因素预测这些结果，并确定未来干预研究的可能目标，以减少种族/民族心理健康差异。

项目成果

Risk reduction for HIV-positive African American and Latino men with histories of childhood sexual abuse.

• DOI: 10.1007/s10508-008-9366-5
• 发表时间: 2008-10
• 期刊: ARCHIVES OF SEXUAL BEHAVIOR
• 影响因子: 3.8
• 作者: Williams, John K.;Wyatt, Gail E.;Rivkin, Inna;Ramamurthi, Hema Codathi;Li, Xiaomin;Liu, Honghu
• 通讯作者: Liu, Honghu

Predictors of somatic symptom severity: The role of cumulative history of trauma and adversity in a diverse community sample.

• DOI: 10.1037/tra0000334
• 发表时间: 2018-09
• 期刊: Psychological trauma : theory, research, practice and policy
• 作者: Loeb TB;Joseph NT;Wyatt GE;Zhang M;Chin D;Thames A;Aswad Y
• 通讯作者: Aswad Y

Intimate partner violence and maternal depression during the perinatal period: a longitudinal investigation of Latinas.

• DOI: 10.1177/1077801210366959
• 发表时间: 2010-05
• 期刊: Violence against women
• 影响因子: 2.2
• 作者: Rodríguez MA;Valentine J;Ahmed SR;Eisenman DP;Sumner LA;Heilemann MV;Liu H
• 通讯作者: Liu H

Cumulative burden of lifetime adversities: Trauma and mental health in low-SES African Americans and Latino/as.

• DOI: 10.1037/a0039077
• 发表时间: 2015-05
• 期刊: PSYCHOLOGICAL TRAUMA-THEORY RESEARCH PRACTICE AND POLICY
• 影响因子: 6.3
• 作者: Myers, Hector F.;Wyatt, Gail E.;Ullman, Jodie B.;Loeb, Tamra B.;Chin, Dorothy;Prause, Nicole;Zhang, Muyu;Williams, John K.;Slavich, George M.;Liu, Honghu
• 通讯作者: Liu, Honghu

Childhood sexual abuse severity and disclosure as predictors of depression among adult African-American and Latina women.

童年性虐待的严重程度和披露是成年非洲裔美国和拉丁裔女性抑郁症的预测因素。

• DOI: 10.1097/nmd.0b013e31822142ac
• 发表时间: 2011
• 期刊: The Journal of nervous and mental disease
• 作者: Sciolla,Andres;Glover,DorothyA;Loeb,TamraB;Zhang,Muyu;Myers,HectorF;Wyatt,GailE
• 通讯作者: Wyatt,GailE