A Triple Quadrupole Mass Spectrometer for the INIA-West Consortium

描述（由申请人提供）：我们是一个由美国国立卫生研究院资助的来自nia - west财团的10名教师调查员组成的小组；我们中的3人在科罗拉多大学丹佛医学院（申请机构），7人在其他机构，包括斯克里普斯研究所、德克萨斯大学奥斯汀分校、德克萨斯理工大学健康科学中心医学院、加州大学圣巴巴拉分校、俄勒冈健康与科学大学和印第安纳大学医学中心。我们正在申请资金购买ThermoElectron TSQ Vantage与Eksigent Ultra 1D Plus NanoLC和Autosampler集成，以进行靶向蛋白质组学测量。该分析系统将扩展科罗拉多大学丹佛医学院可用的质谱资源，并致力于支持nia - west联盟的研究目标。

DESCRIPTION (provided by applicant): We are a group of ten NIH-funded faculty investigators from the INIA-West Consortium; three of us are at the University of Colorado Denver School of Medicine (applicant institution) and seven are at other institutions including the Scripps Research Institute, University of Texas Austin, Texas Tech University Health Sciences Center School of Medicine, University of California Santa Barbara, Oregon Health and Science University, and Indiana University Medical Center. We are requesting funds to purchase a ThermoElectron TSQ Vantage integrated with the Eksigent Ultra 1D Plus NanoLC and Autosampler to make targeted proteomic measurements. This analytical system will expand the mass spectrometry resources available at the University of Colorado Denver School of Medicine and be dedicated to support the research objectives of the INIA-West Consortium. PUBLIC HEALTH RELEVANCE: The INIA-West Consortium consists of a group of multidisciplinary investigators with the common goal of discovering the underlying molecular mechanisms contributing to alcohol addiction. The requested instrumentation is critical to meeting our analytical requirements and will greatly impact the quality and productivity of our research.