Geriatric Oncology Research to Improve Clinical Care

描述（由申请人提供）：这是一份为期五年的U13合作会议拨款的初步申请，题为“老年肿瘤学研究以改善临床护理”，代表癌症和衰老研究小组（CARG）与国家衰老研究所（NIA）和国家癌症研究所（NCI）的老年病学和临床老年学分支合作提交。本次会议资助计划的使命是为老年病学和肿瘤学的多学科研究团队提供一个论坛，以审查老年肿瘤学目前的证据水平，确定最高研究优先领域，并制定研究方法，以改善未来10年内老年癌症患者的临床护理。随着美国人口迅速老龄化，需要癌症治疗的老年人数量也急剧增加；然而，在制定肿瘤治疗标准的临床试验中，这一不断增长的人群的代表性仍然不足。有必要制定一项研究议程，最大限度地发挥老年病学和肿瘤学之间的协同作用，确定研究的最高优先领域，并改进研究方法，加强这两个领域之间的合作。本次会议奖助金的目标是：1。确定老年肿瘤学目前的证据水平和高度优先研究的领域。从老年病学和肿瘤学领域确定研究方法的优势，这些优势可以应用和整合到涉及老年癌症患者的研究中。促进多学科学术团队之间的合作，重点是在老年肿瘤学研究中使用共享的研究方法。培养和促进老年肿瘤学领域现有和新的研究人员的研究。传播本次会议的研究成果，并提出易于适应的建议，以加强老年肿瘤学研究方法。相关系列会议的拟议主题包括：衰老和癌症研究界面的生物学、临床和社会心理相关因素。老年和/或体弱成人癌症治疗性临床试验的设计和实施。干预研究的设计和实施，以维持或改善老年和/或体弱成人癌症患者的生存质量。这三次拟议的会议将相互建立，最初的会议有助于调整后续会议的计划和结构。该系列会议将由NIA、NCI和CARG以及其他致力于老年病学和/或肿瘤学的组织（AGS、ASCO、SIOG、AACR）的成员组成的监督委员会领导。每次会议都将设立一个项目委员会，负责与每次会议主题相关的内容和流程、会议的交付和成果的传播。

DESCRIPTION (provided by applicant): This is an initial application for a five-year U13 cooperative conference grant titled "Geriatric Oncology Research to Improve Clinical Care", submitted on behalf of the Cancer and Aging Research Group (CARG) in collaboration with the Geriatrics and Clinical Gerontology branch of the National Institute on Aging (NIA) and the National Cancer Institute (NCI). The mission of this conference grant program is to provide a forum for a multidisciplinary team of investigators in geriatrics and oncology to review the present level of evidence in geriatric oncology, identify areas of highest research priority, and develop research approaches to improve clinical care for older adults with cancer within the next 10 years. As the US population rapidly ages, the number of older adults needing cancer treatment also increases dramatically; however, this growing population continues to be underrepresented in clinical trials that set the standards for oncology care. There is a need to develop a research agenda that maximizes the synergy between geriatrics and oncology, to identify areas of highest research priority, and to refine research approaches that enhance collaboration between both fields. The goals of this conference grant are: 1. To identify the present level of evidence and areas of high research priority in geriatric oncology 2. To identify strengths in research methodology, from the fields of geriatrics and oncology, that can be applied and integrated into research studies involving older adults with cancer 3. To foster collaboration between multidisciplinary scholarly teams, with a focus on shared research methods to be utilized across studies in geriatric oncology 4. To foster and promote the research of existing and new investigators in geriatric oncology 5. To disseminate findings from this conference grant program with easily adaptable recommendations to strengthen geriatric oncology research methodology. Proposed topics for the linked conference series include: 1. Biological, Clinical, and Psychosocial Correlates at the Interface of Aging and Cancer Research. 2. Design and Implementation of Therapeutic Clinical Trials for Older and/or Frail Adults with Cancer. 3. Design and Implementation of Intervention Studies to Maintain or Improve the Quality of Survival of Older and/or Frail Adults with Cancer. These three proposed conferences will build upon one another, with initial meetings helping to fine-tune the program and structure of subsequent meetings. The conference series will be led by an Oversight Board consisting of members from the NIA, NCI, and CARG, as well as other organizations dedicated to geriatrics and/or oncology (AGS, ASCO, SIOG, AACR). Each conference will have a Program Committee that will be responsible for content and processes related to the topic of each conference, for delivery of the conference, and dissemination of the findings. PUBLIC HEALTH RELEVANCE: The mission of this U13 conference grant, entitled "Geriatric Oncology Research to Improve Clinical Care," is to provide a forum for a multidisciplinary team of investigators in geriatrics and oncology to review the present level of evidence in geriatric oncology, identify areas of highest research priority, and develop research approaches, within the next 10 years, to improve clinical care for older adults with cancer.