Administrative Core

行政核心的目的是确保有效的全面管理和协调， 中心。为了实现这些目标，行政核心（核心A）分为四个具体部分， 目标：1]跟踪每个项目和核心的科学进展和成就，2] 确定并确保不同现场的相关研究协调，3]确保遵守 IRB和其他监管机构对人类受试者的研究，和4]制定行政管理 指导方针（包括分包合同），以界定研究者的责任，并确保 负责任的资金管理。第一个目标是跟踪《里程碑》和《时间表》的进展情况 由各个项目和核心开发。这将通过使用电子 （基于网络的）交流、电话会议、现场访问、面对面会议、区域科学 交流和短期培训。第二个目标的基本原理是， 外地办事处之间共同（共享）的成功和障碍是本RFA的重要理由， 发展疟疾研究国际卓越中心。第三个目标的理由是， 大量的指导方针和权威机构规范了人类研究的表现， 这些研究成功的潜在障碍。此问题将通过雇用合规人员来解决 通过在每个参与研究中心提供类似的工作人员支持， 第四个目标的理由是，由于国际社会的参与，资金的管理更加困难。 项目将通过提供支持以确保及时转移资金来应对这一挑战 在机构之间，通过电子报告支出，并借鉴模板， 过去成功地用于分包合同。行政核心的长期目标是：1] 在西非和中非发展研究管理专门知识，2]提供区域领导 关于与卫生研究有关的行政问题，3]提供了从能力 建立（个人培训）研究机构和网络。

The purpose of the administrative core is to ensure the effective overall administration and coordination of the Center. To accomplish those goals, the Administrative Core (Core A) has been organized in four specific aims: 1] Track scientific progress and accomplishments for each of the individual projects and cores, 2] Identify and ensure the coordination of related studies at different field sites, 3] Ensure compliance with IRBs and other regulatory authorities for studies of human subjects, and 4] Develop administrative guidelines (including subcontracts) to define the responsibilities of investigators, and to ensure the responsible management of funds. The first objective is to track progress on the Milestones and Timelines developed by the individual projects and cores. This will be accomplished using a combination of electronic (WEB-based) communications, conference calls, site visits, face-to-face meetings, regional scientific interchanges and short-term training. The rationale forthe second objective is that the identification of common (shared) successes and obstacles among field sites is an important justification for this RFA to develop International Centers of Excellence for Malaria Research. The rationale for the third objective is that the enormous number of guidelines and authorities which regulate the performance human studies is a potential obstacle to the success of these studies. This issue will be addressed by hiring a Compliance Officer within the Administrative Core and by providing similar staff support at each of the participating sites. The rationale for the fourth objective is that the management of funds is more difficult with international projects. That challenge will be addressed by providing support to ensure the timely transfers of funds among institutions, by electronic reporting of expenditures, and by drawing on templates that have been used successfully in the past for subcontracts. The long-term objectives of the Administrative Core are to: 1] develop expertise in research administration within West and Central Africa, 2] provide regional leadership on administrative issues related to health research and 3] provide a foundation to move from capacity building (training of individuals) to the development of research institutions and networks.