A LONGITUDINAL STUDY OF SUBSTANCE ABUSE AND HIV RISK AMONG ADULT LATINA MOTHER-DA

描述（由申请人提供）：美国拉丁裔妇女的艾滋病毒感染率是非拉丁裔白人妇女的六倍。拉丁裔正在遭受物质使用障碍带来的各种负面影响，包括亲密伴侣暴力、监禁、无家可归和疾病。我们的长期目标是减少拉丁美洲人中艾滋病毒发病率和药物滥用相关的健康差距。本应用程序的目标是实现这一目标的重要一步，目的是确定以社区为基础的拉丁裔母亲和女儿样本的物质使用（合法和非法）和艾滋病毒风险行为轨迹如何受到家庭机制变化的影响（母女合作或依恋），文化进程，以及药物滥用和艾滋病毒风险行为的其他社会决定因素。研究设计包括四波数据收集。基线数据是在NIDA资助的拉丁裔母亲和女儿的代际药物使用和艾滋病毒风险行为的横断面试点研究中收集的（R24DA014260, PI: Mario De La Rosa, Ph.D.）。在基线评估的基础上，提出了三项新的纵向评估。第一次新的随访评估将与原始研究的基线评估间隔约5年。其余两次随访评估将在前一次随访评估1年后进行。我们的第一个目标是确定文化和社会决定因素对以社区为基础的拉丁裔母亲和女儿的物质使用和艾滋病毒风险行为变化轨迹的影响。工作假设是拉丁裔母亲和女儿经历(1)更多的文化适应美国文化；(2)社会经济条件较差；(3)失去人际支持；(4)宗教参与较少；（五）参与刑事司法；(6)亲密伴侣暴力；(7)与就业、关系和/或居住相关的慢性压力较大；或(8)心理健康和医疗状况下降，因为他们的基线评估将显示在7年评估期间高药物使用率和艾滋病毒风险行为的增加或维持。我们的第二个目标是确定母女依恋对物质使用和艾滋病毒风险行为变化轨迹的影响。在7年的时间里，增加依恋水平或持续保持高依恋水平的拉丁裔母亲和女儿将报告减少或持续降低药物使用和艾滋病毒风险行为的水平。我们的第三个目标是确定母女依恋在有害社会决定因素的经历与物质使用和艾滋病毒风险行为的变化轨迹之间的关联中的调节作用。

DESCRIPTION (provided by the applicant): The HIV contraction rate for Latina women in the U.S. is six times the rate for non-Latina, White women. Latinas are suffering disparate negative consequences from substance use disorders, including intimate partner violence, incarceration, homelessness, and medical ailments. Our long-term goal is to reduce the incidence of HIV and substance abuse related health disparities among Latinas. The objective of this application, which is a significant step in pursuit of this goal, is to determine how substance use (both licit and illicit) and HIV risk behavior trajectories of a community-based sample of Latina mothers and daughters are influenced by changes in familial mechanisms (mother-daughter acoplamiento or attachment), cultural processes, and other social determinants of substance abuse and HIV risk behaviors over time. The study design involves four waves of data collection. Baseline data were collected in a cross-sectional pilot study of intergenerational drug use and HIV risk behaviors among Latina mothers and daughters funded by NIDA (R24DA014260, PI: Mario De La Rosa, Ph.D.). Three new longitudinal assessments are proposed to follow-up on baseline assessment. The first new follow-up assessment will be spaced approximately 5 years from the original study's baseline assessment. The remaining two follow-up assessments will occur 1 year from the preceding follow-up assessment. Our first aim is to determine the influence of cultural and social determinants on trajectories of change for substance use and HIV risk behaviors among a community-based sample of Latina mothers and daughters. The working hypothesis is that Latina mothers and daughters who experience (1) more acculturation to U.S. culture; (2) poorer socioeconomic conditions; (3) a loss of interpersonal supports; (4) less religious involvement; (5) involvement with the criminal justice system; (6) intimate partner violence; (7) greater employment, relationship, and/or residential related chronic stress; or (8) declining mental health and medical status since their baseline assessment will exhibit either an increase in or maintenance of high rates of substance use and HIV risk behaviors over the 7 year assessment time period. Our second aim is to determine the influence of mother-daughter attachment on trajectories of change for substance use and HIV risk behaviors. Latina mothers and daughters who either increase their levels of attachment or maintain consistently high levels of attachment will report reduced or consistently lower levels of substance use and HIV risk behaviors over a 7 year time period. Our third aim is to determine the moderating role of mother-daughter attachment on associations between experiences of detrimental social determinants and trajectories of change for substance use and HIV risk behaviors.