Environment and Perceived Control: Improving Sleep in Hospitalized Older Patients

描述（由申请人提供）：本申请的目的是支持芝加哥大学奖学金培训的学术住院医师Vineet Arora（医学博士，MA）以患者为导向的研究计划和职业发展。Arora博士的总体目标是发展成为一名独立的研究者，专注于描述和改善老年住院患者的睡眠时间和睡眠质量。Arora博士将在Eve货车Cauter博士的指导下发展她的研究技能，Eve Cauter博士是正常和病理状态下睡眠和昼夜节律的着名权威，专注于老年人的睡眠。大卫梅尔泽，医学博士，博士，一个有成就的研究人员在医院医学和卫生经济学的重点是老龄化，将担任共同导师。阿罗拉博士还将受益于包括格雷格·萨克斯博士、埃里克·科尔曼博士和丹尼尔·布劳纳博士在内的顾问团队在老年人临床护理和研究方面的集体专业知识。她还将从一个合作者团队获得必要的培训和研究技能，包括：（1）Babak Mokhlesi，医学博士，睡眠医学奖学金主任，他将使Arora博士获得睡眠医学的正式培训;（2）Kristen Knutson，博士，研究教师和人类学家，专门使用活动记录仪和睡眠量表来量化睡眠时间和质量;（3）Anirban Basu博士，统计分析专家。在拟议的奖项期间，阿罗拉博士将通过芝加哥大学的结构化课程和课程作业获得睡眠医学、健康服务研究和老年医学方面的正式培训。本研究提案的总体目标是阐明环境、医疗保健和患者因素以及患者感知控制水平如何影响住院老年患者的睡眠时间和睡眠质量。此外，住院老年患者的住院睡眠（持续时间和质量）和结果（体力活动和其他健康结果）之间的关系将被表征。通过这段时间的职业发展和研究，Arora博士将能够更好地了解住院睡眠的决定因素和影响，从而能够设计以证据为基础的干预措施，旨在改善住院老年人的住院睡眠和相关结果。 公共卫生相关性：本研究提案的总体目标是阐明环境、医疗保健和患者因素以及患者感知控制水平如何影响住院老年患者的睡眠时间和睡眠质量。此外，住院老年患者的住院睡眠（持续时间和质量）和结果（体力活动和其他健康结果）之间的关系将被表征。通过这段时间的职业发展和研究，Arora博士将能够更好地了解住院睡眠的决定因素和影响，从而能够设计以证据为基础的干预措施，旨在改善住院老年人的住院睡眠和相关结果。

DESCRIPTION (provided by applicant): The purpose of this application is to support the patient-oriented research program and career development of Vineet Arora, MD, MA, a fellowship-trained academic hospitalist at the University of Chicago. Dr. Arora's overall goal is to develop into an independent investigator with a focus on characterizing and improving sleep duration and sleep quality for older hospitalized patients. Dr. Arora will develop her research skills under the mentorship of Eve Van Cauter, PhD, a well-known authority on sleep and circadian rhythms in normal and pathologic states, with a focus on sleep in older persons. David Meltzer, MD, PhD, an accomplished investigator in research in hospital medicine and health economics with a focus on aging, will serve as a co- mentor. Dr. Arora will also benefit from the collective expertise in clinical care and research of older persons from a team of advisors, including Drs. Greg Sachs, Eric Coleman, and Daniel Brauner. She will also obtain necessary training and research skills from a team of collaborators including: (1) Babak Mokhlesi, MD, Director of the Sleep Medicine Fellowship, who will enable Dr. Arora to obtain formal training in sleep medicine; (2) Kristen Knutson, PhD, a research faculty and anthropologist who specializes in the use of actigraphy and sleep scales to quantify sleep duration and quality; and (3) Anirban Basu, PhD, an expert in statistical analysis. During the proposed award, Dr. Arora will obtain formal training in sleep medicine, health services research, and geriatrics through structured curricula and coursework at the University of Chicago. The overall goal of this research proposal is to elucidate how environmental, healthcare, and patient factors, in addition to a patients' level of perceived control, impact sleep duration and sleep quality in hospitalized older patients. In addition, the relationship between inpatient sleep (duration and quality) and outcomes (physical activity and other health outcomes) for hospitalized older patients will be characterized. Through this period of career development and research, Dr. Arora will be able to better understand the determinants and effects of in- hospital sleep which can enable the design of evidence-based interventions that aim to improve in-hospital sleep and associated outcomes for hospitalized older adults. PUBLIC HEALTH RELEVANCE: The overall goal of this research proposal is to elucidate how environmental, healthcare, and patient factors, in addition to a patients' level of perceived control, impact sleep duration and sleep quality in hospitalized older patients. In addition, the relationship between inpatient sleep (duration and quality) and outcomes (physical activity and other health outcomes) for hospitalized older patients will be characterized. Through this period of career development and research, Dr. Arora will be able to better understand the determinants and effects of in-hospital sleep which can enable the design of evidence-based interventions that aim to improve in-hospital sleep and associated outcomes for hospitalized older adults.