Long-Term Consequences of Lymphoma and its Treatment

本方案的目的是招募多达300名有兴趣参与NIA研究的受试者，作为NIH既往癌症治疗随访的一部分。 既往在NIH接受过非霍奇金淋巴瘤或霍奇金病治疗的受试者有资格参加本研究。 本方案的招募将通过联系先前签署了NIH淋巴瘤研究治疗知情同意书的受试者进行。 本方案的联系人为NIA临床研究部门。 完成电话知情同意并获得随访信息。 可以通过电话交谈要求健康史总结;实际体检可能不是在所有情况下都需要。 如果患者愿意在研究中心参加本研究，可能会要求他/她前往位于Harbor Hospital，巴尔的摩，马里兰州的NIA临床研究单位参加随访评价。 在现场进行的评价/测试： 获得知情同意。 血液检查作为评估过程的一部分进行，包括全血细胞计数（CBC），血清化学，肝肾功能，甲状腺功能和其他常规检查。病毒学检测可能包括在组合中;如果进行HIV（AIDS）检测，将使用单独的同意书。一些血液也可能用于其他医院临床实验室可能无法提供的研究测试，并且尚未确定其临床意义。由于尚不清楚临床意义或意义，因此不会向患者报告研究血液检查结果。 抽取的血液量不会超过100 cc（少于7汤匙）。 尿检：尿检可能包括常规尿分析，以测量肾功能。 健康史和/或体格检查：可能要求提供受试者病历的详细总结，并在研究访视前书面发布病历。 NIA的医生或执业护士与他们一起审查参与者的病史，并进行体检，其中包括标准的心理问卷。 特别注意治疗的长期后遗症。 主要研究者与受试者讨论结果（实验室和体格检查等），并根据诊断和治疗提供有关健康问题和风险的信息。 收集和分析长期生存信息。 还将收集和分析死亡率信息。 今年没有出版物。

The intent of this protocol is to accrue up to 300 subjects who are interested in participating in NIA research studies as part of follow-up for previous cancer treatment at NIH. Subjects previously treated for Non-Hodgkins's lymphoma or Hodgkin's disease at the NIH are eligible for this study. Recruitment for this protocol will be through contact with participants who have previously signed informed consent for treatment on NIH study for lymphoma. Contact for this protocol is through the NIA Clinical Research Unit. A telephone consent is completed and follow-up information is obtained. A health history summary may be requested by phone conversation; actual physical exam may not be required in all cases. If a patient is willing to participate on site for this study, he/she may be asked to come to the NIA Clinical Research Unit located at Harbor Hospital, Baltimore, Maryland to participate in a follow-up evaluation. Evaluation/tests that are performed on site: Informed consent is obtained. Blood tests are performed as part of the evaluation process, including complete blood counts (CBC), serum chemistries, liver and kidney function, thyroid function and other routine tests. Virology tests may be included in the battery; If an HIV (AIDS) tests is performed, a separate consent will be used. Some of the blood may also be used for research tests that may not be available in other hospital clinical labs and for which no clinical significance has been determined. The results of research blood tests will not be reported to the patient as the clinical significance or meaning is not known. The amount of blood drawn will not exceed 100cc (less than 7 tablespoons). Urine Tests: Urine tests may include a routine urinalysis to measure kidney function. Health History and/or Physical Examination: A detailed summary of the subjects medical record may be requested, with written release of medical records prior to the study visit. A physician or nurse practitioner of the NIA reviews the participants medical history with them and performs a physical examination, which includes standard psychological questionnaires. Particular attention to long-term sequelae of treatment is paid. The Principal Investigator discusses the findings (laboratory and physical exam, etc) with the participant and provides information regarding health issues and risks based on the diagnoses and treatments. Long term survival information is collected and analyzed. Morbidity information will also be collected and analyzed. There are no publications this year.