Transplant Surgery Scientist Training Program

描述(由申请者提供)：移植有望逆转数千名美国人的临床进程，这些人患有终末期器官疾病和代谢性疾病。西北大学的移植项目在临床移植和移植相关研究方面处于全国领先地位。近年来，从事移植相关研究的移植外科医生和内科医生的数量有所减少。研究相关职业缺乏热情的原因包括1)对研究培训的财政支持不足，2)临床专业和超专业培训和研究培训之间的冲突，3)严格的研究方法论教学不足，4)项目主任缺乏责任感，以确保致力于临床研究职业的受训者在他们的研究培训期间从事提高他们的竞争力的活动，以获得独立的资助。这笔培训补助金的具体目标是：1)为受训者提供津贴支持；2)由初级、中级和高级研究人员与精通移植的学术临床医生合作提供指导；3)保护受训者不受争抢时间的临床活动的影响；4)维持一个扩大候选者人种多样性和质量的管理结构；5)提供跨度跨度的培训机会。 从基础/转化科学到临床/结果研究，在与临床移植的交叉点上；以及6)继续进行持续的评估过程，以确定该计划是否达到其目标和目的。受训者将接触到严格的课堂学习基础，学习成功进行移植相关研究所必需的学科，同时接触到移植手术的其他各个方面。学员可以选择两种不同的途径：NUTORC(西北大学移植成果研究合作)和NUCTRIBE(西北大学免疫生物学和生物医学工程移植研究合作)。两者都提供由多学科的高级、中级和初级导师进行的密集、严格的培训，以及课堂教育。NUTORC的学员可以在卫生服务和结果研究硕士、临床调查硕士、流行病学和生物统计学硕士或医疗质量和患者安全硕士之间进行选择。NUCTRIBE学员可以从与他们的研究相关的许多学科中选择课程，这些课程是在他们的导师和执行委员会咨询和批准后选择的。这两个途径都需要在负责任的研究行为中进行课程学习。这两个轨道都为受训人员提供了独特的准备，使他们能够在与移植相关的领域进行创新的、最先进的研究。

DESCRIPTION (provided by applicant): Transplantation holds the promise of reversing the clinical course of thousands of Americans afflicted with end- stage organ disease, as well as metabolic diseases. Northwestern University's transplant program is a national leader in both clinical transplantation and transplantation-related research. The number of transplant surgeons and physicians engaged in transplantation-related research had decreased in recent years. Reasons given for the lack of enthusiasm in pursuing a research-related career include 1) insufficient financial support for research training, 2) conflict between clinical specialty and su-specialty training and research training, 3) inadequate teaching of rigorous research methodology, and 4) the lack of accountability on the part of program directors to ensure that trainees committed to careers in clinical investigation are engaged in activities during their research training that enhance their competitiveness to obtain independent funding when they become faculty members. The specific objectives of this training grant are to 1) provide stipend support for trainees; 2) provide mentorship by junior, mid-level, and senior investigators in collaboration with academic clinicians well versed in transplantation; 3) protect trainees from clinical activities that compete for their time; 4) sustain an administrative structure that expand the ethnic diversity and quality of the candidate pool; 5) provide training opportunities that span the spectrum from both basic/translational science to clinical/outcomes research at their intersection with clinical transplantation; and 6) continue an ongoing evaluation process for determining whether or not the program is meeting its goals and objectives. Trainees will be exposed to a rigorous base of classroom study in the disciplines necessary for successfully conducting transplant-related research, while being exposed to various other aspects of transplant surgery. There are two different tracks trainees can select from: NUTORC (the Northwestern University Transplant Outcomes Research Collaborative) and NUCTRIBE (the Northwestern University Collaborative for Transplant Research in Immunobiology and Biomedical Engineering). Both provide intensive, rigorous training by multidisciplinary senior, mid-level, and junior mentors, as well as classroom education. NUTORC trainees may choose between an MS in Health Services and Outcomes Research, an MS in Clinical Investigation, an MS in Epidemiology and Biostatistics or an MS in Healthcare Quality and Patient Safety. NUCTRIBE trainees may select coursework from many disciplines related to their research, chosen after consultation and approval by their mentors and the Executive Committee. Both tracks are required to take coursework in the responsible conduct of research. Both tracks uniquely prepare trainees to perform innovative, state-of-the-art research in transplant-related fields.