NAVBO Workshops at Vascular Biology 2014

描述(由申请人提供)： 近年来，血管生物学领域经历了信息量的爆炸式增长。鉴于这些丰富的信息，越来越需要进行讨论和跨学科 思想交流。血管生物学在过去十年中已经发展成为一个主要的跨学科领域，影响着人类的许多主要疾病，包括动脉粥样硬化、高血压、癌症、神经疾病、糖尿病、中风和血液病。最近，炎症已经成为血管生物学中的一个关键话题，对血管疾病有重大影响，与血管发育和遗传学有重要的交叉，包括在新兴的血管再生领域。血管炎症是血管生物学中的一个新兴课题。对公众健康有很大影响的血管疾病，如高血压和动脉粥样硬化，具有重要的炎症和免疫成分。此外，血管炎症影响血管生成、干细胞生物学、再生和血管分化。因此，第六届NAVBO血管发育生物学研讨会将与第一届NAVBO血管炎症研讨会同时举行，目前包括一个遗传成分。这次联合会议将使科学家们聚集在一起，共同关心了解血管发育过程以及这些信息如何与病理状态相关。该计划旨在包括这两个领域感兴趣的传统主题中的最新未出版信息，并在每个领域和这些以前不同领域的交叉点整合新的、新兴的主题。 在此申请中，我们申请资金以部分支持这两个跨学科的国际研讨会，这些研讨会将汇集来自学术和私营部门的研究人员、博士后研究员和来自不同研究领域的研究生，为期四天。 紧张的讨论和学习。会议将于2014年10月19日至23日在加利福尼亚州太平洋格罗夫的Asilomar会议场地举行。我们已经收集了一份演讲者名单，反映了发育生物学、遗传学和炎症领域的领导者，因为这些问题与血管系统有关。此外，讲习班上大约一半的演讲者将从提交的摘要中挑选出来，以获取这些学科中最新的未发表作品。大部分的抽象陈述将来自早期调查人员和受训人员。我们的目标是促进不同调查人员之间的高层思想交流，包括直接参与翻译研究的调查人员。我们还包括翻译生物学和血管治疗学的联合会议，以促进参与基础和临床/翻译研究的研究人员之间的互动。这次会议寻求可能的新治疗方法来改善广泛的病理状态，包括发育缺陷、高血压、癌症、心肌梗死和中风。

DESCRIPTION (provided by applicant): The field of vascular biology has experienced an explosion of information in recent years. In light of this wealth of information there is an increased need for discussion and interdisciplinary exchange of ideas. Vascular biology has evolved over the past decade as a major cross-disciplinary field that impacts on a wide number of major human diseases, including atherosclerosis, hypertension, cancer, neurological disorders, diabetes, stroke, and hematological disorders. More recently, inflammation has emerged as a critical topic in vascular biology with major implications for vascular disease and with important intersections with vascular development and genetics, including in the emerging field of vascular regeneration. Vascular inflammation is an emerging topic in vascular biology. Vascular diseases with a large public health impact such as hypertension and atherosclerosis have significant inflammatory and immune components. In addition, vascular inflammation impacts on angiogenesis, stem cell biology, regeneration, and vascular differentiation. Therefore, the sixth NAVBO Developmental Vascular Biology Workshop, now including a genetic component, will be held concurrently with the first ever NAVBO Vascular Inflammation Workshop. This joint conference will bring together scientists with the common interest of understanding the process of blood vessel formation in development and how this information pertains to pathological states. The program was developed to include the latest unpublished information in traditional topics of interest in both o these fields and to integrate novel, emerging themes in each area and at the intersection of these previously diverse areas. In this application we request funds to partially support both of these interdisciplinary, international workshops, which will bring together investigators from the academic, and private sectors, post-doctoral fellows, and graduate students from diverse fields of study for four days of intense discussion and study. The conference will be held at the Asilomar Conference Grounds in Pacific Grove, CA from October 19-23, 2014. We have assembled a roster of speakers that reflects the leaders in developmental biology, genetics, and inflammation as those issues pertain to the vasculature. In addition, approximately half of the speakers at the workshops will be chosen from submitted abstracts in order to capture the latest unpublished work in these disciplines. The majority of abstract presentations will be from early stage investigators and trainees. It is our aim to foster a high-level exchange of ideas among a diverse group of investigators, including investigators directly involved in translational research. We have included joint sessions on translational biology and vascular therapeutics to facilitate interactions among researchers involved in basic and clinical/translational research. The conference seeks insight into possible new therapeutic approaches for amelioration of a broad spectrum of pathological states, including developmental defects, hypertension, cancer, myocardial infarction, and stroke.