Border Biomedical Research Center

描述（由申请人提供）：边境生物医学研究中心（BBRC）。德克萨斯大学埃尔帕索分校（UTEP）与区域学术，政府和私人团体合作，以维持和发展现有的BBRC基础设施和计划为目标，以实现对美国普遍存在的健康差异的高质量研究墨西哥边境。这一目标将通过实现四个具体目标来实现。主要包括：（1）加强三个研究领域的研究力度，以更好地理解原因和机制。这些“集群”是（a）传染病和免疫，（B）癌症和环境毒物引起的疾病，以及（c）不同的神经调节障碍。追求将更加强调流行病学和与临床和公共卫生专家的合作。(2)加强研究基础设施，以提高越来越多的调查人员的能力，具体做法是：（a）加强分子和细胞生物学研究以及生物统计学和生物信息学咨询方面的多用户核心设施，（B）制定一项新的倡议，即社区参与核心，（c）招聘新的教职人员研究边境卫生问题，（d）从专业角度培养边界研究中心调查人员，（e）实施一项强调跨学科研究的试点赠款计划，以及（f）建立一个全机构范围的研讨会和两年一次的国际专题讨论会，通过实践强调BBRC对社区参与、网络、合作和转化研究的高度重视。基础设施的增强包括支持研究的物理工厂组件，协调，管理和治理计划组件的行政核心，以及评估实现计划和边境健康目标的进展情况的评估组件。(3)通过在各种BBRC活动，包括教学，基础科学和应用科学之间的相互作用和实验室发现的实用性的重要性更加强调BBRC研究的翻译。(4)创建，通过集体BBRC活动，一个具有全国竞争力的研究环境，以支持生物科学博士课程作为一种手段，以发展未来的研究人员和扩大调查人力。

DESCRIPTION (provided by applicant): Border Biomedical Research Center (BBRC). The University of Texas at El Paso (UTEP), in collaboration with regional academic, governmental and private groups, has as a goal, to sustain and grow extant BBRC infrastructure and programs to enable high quality research on health disparities prevalent on the U.S. Mexico border. This goal will be obtained through achievement of four specific objectives. These are to: (1) Focus on augmenting three research areas of strength to better understand causes and mechanisms. These "clusters" are (a) infectious diseases and immunity, (b) cancer and diseases caused by environmental toxicants, and (c) distinct neuro-modulation disorders. Pursuits will be with greater emphasis on epidemiology and collaborations with clinical and public health specialists. (2) Strengthen research infrastructure to enhance capabilities of growing numbers of investigators through (a) enhancement of multi-user core facilities for research in molecular and cell biology and consultation in biostatistics and bioinformatics, (b) creation of a new initiative, the Community Engagement Core, (c) recruitment of new faculty members to research border health issues, (d) development, professionally, of BBRC investigators, (e) implementation of a pilot grant program emphasizing inter-disciplinary research, and (f) establishment of an institution-wide seminar and a biennial international symposium that underscore through practice BBRC's heightened emphasis on community engagement, networking, collaboration and translational research. Included in infrastructure enhancement are physical plant components that support research, an administrative core to coordinate, manage and govern program components, and an evaluative component to assess progress in achieving program- and border health objectives. (3) Accentuate translation of BBRC research through greater emphasis in various BBRC activities, including teaching, of the interplay between basic and applied science and the importance of utility in laboratory discoveries. (4) Create, through collective BBRC activities, a nationally competitive research environment to support the doctoral program in Biological Sciences as a means to develop future researchers and amplify investigative manpower.