Pathological and therapeutic antibody production

该计划赠款汇集了一个世界领先的专家团队，以阐明通过制造抗体来保护大多数人免受感染的机制，以及他们的失败是由基因或流感或艾滋病毒等感染引起的。该团队将确定保护大多数人免受针对身体正常部位的抗体的机制，正常部位的抗体失效会导致包括类风湿性关节炎在内的许多自身免疫性疾病。该团队将开发出制造更好抗体的方法。

This Program Grant brings together a world-leading team of experts to elucidate mechanisms that protect most people from infection by making antibodies, and their failure caused by genes or infections like influenza or HIV. The team will determine mechanisms that protect most people from making antibodies against normal parts of our body, whose failure causes numerous autoimmune diseases including rheumatoid arthritis. The team will develop ways to engineer better antibodies.