Afinity maturation and development of an anti-inflammatory monoclonal antibody
Afinity maturation and development of an anti-inflammatory monoclonal antibody
批准号:
nhmrc : 535931
负责人:
A/Pr Daniel Christ
金额:
$25.84万
依托单位国家:
澳大利亚
项目类别:
Career Development Fellowships
财政年份:
2009
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2009-01-01 至 2012-12-31
中文摘要
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英文摘要
Antibodies are a relatively new class of drugs that directly target molecular mechanisms of disease. Antibody therapies, such as the breast cancer drug Herceptin, have significantly increased our arsenal of effective therapeutics. In collaboration with G2 Therapies, we will use cutting-edge genetic engineering technology to produce fully human antibodies for the treatment of inflammatory diseases, such as rheumatoid arthritis.
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会议论文
Next Generation Antibody Therapeutics
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批准号:nhmrc : GNT1157744
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项目类别:Research Fellowships
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资助金额:$71.73万
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财政年份:2019
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负责人:A/Pr Daniel Christ
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依托单位:
Pathological and therapeutic antibody production
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批准号:nhmrc : 1113904
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项目类别:Program Grants
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资助金额:$627.93万
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财政年份:2017
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负责人:A/Pr Daniel Christ
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依托单位:
Pathological and therapeutic antibody production
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批准号:nhmrc : GNT1113904
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项目类别:Programs
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资助金额:$918.42万
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财政年份:2017
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负责人:A/Pr Daniel Christ
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依托单位:
Positive and negative selection in the germinal centre reaction
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批准号:nhmrc : GNT1105875
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项目类别:Project Grants
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资助金额:$129.0万
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财政年份:2016
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负责人:A/Pr Daniel Christ
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依托单位:
Development of stable human antibody phage display libraries
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批准号:nhmrc : GNT1113790
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项目类别:Development Grants
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资助金额:$53.96万
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财政年份:2016
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负责人:A/Pr Daniel Christ
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依托单位:
Development of stable human antibody phage display libraries
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批准号:nhmrc : 1113790
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项目类别:Development Grants
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资助金额:$36.75万
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财政年份:2016
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负责人:A/Pr Daniel Christ
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依托单位:
Positive and negative selection in the germinal centre reaction
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批准号:nhmrc : 1105875
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项目类别:Project Grants
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资助金额:$88.95万
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财政年份:2016
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负责人:A/Pr Daniel Christ
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依托单位:
Stability engineering of human antibody therapeutics
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批准号:nhmrc : 1076356
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项目类别:Development Grants
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资助金额:$28.08万
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财政年份:2014
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负责人:A/Pr Daniel Christ
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依托单位:
Development of monoclonal antibody therapy
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批准号:nhmrc : 1050146
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项目类别:Career Development Fellowships
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资助金额:$30.62万
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财政年份:2013
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负责人:A/Pr Daniel Christ
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依托单位:
Development of a therapeutic monoclonal antibody
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批准号:nhmrc : 1056567
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项目类别:Development Grants
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资助金额:$38.64万
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财政年份:2013
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负责人:A/Pr Daniel Christ
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依托单位:
Development of a humanised antibody to MIC-1/GDF15 for therapy of anorexia/cachexia of cancer
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批准号:nhmrc : 1017594
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项目类别:Development Grants
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资助金额:$39.16万
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财政年份:2011
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负责人:A/Pr Daniel Christ
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依托单位:
国内基金
海外基金
TMEM30A介导的磷脂酰丝氨酸外翻促进毛细胞-SGN突触发育成熟的机制研究
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批准号:82371172
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项目类别:面上项目
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资助金额:49.00万元
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批准年份:2023
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负责人:杨光
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依托单位:
神经胶质成熟因子-β对肝星状细胞活化和肝纤维化的影响及其机制研究
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批准号:30800508
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项目类别:青年科学基金项目
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资助金额:19.0万元
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批准年份:2008
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负责人:饶慧瑛
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依托单位: