The contributions of different sources of calcium to the induction of long term potentiation

当我们制造记忆时，我们会改变神经细胞之间突触连接的强度。这些变化在河马区尤为明显，河马区是大脑中参与形成记忆的区域。如果突触连接的强度足以激活神经元，导致钙离子水平上升，那么突触连接的强度就会改变。钙可以从神经元内的几个来源获得。该项目旨在评估这些不同的钙来源在诱导突触强度增加方面的相对重要性。

When we make memories, we alter the strength of synaptic connections between nerve cells.These changes are particularly marked in the hippopcampus ; a region of the brain involved in the formation of memories. The strength of a synaptic connection is altered if it activates a neurone sufficiently to cause a rise in the level of calcium ions. Calcium can be derived from several sources within the neurone. This project aims to assess the relative importance of these different sources of calcium in inducing increases in synaptic strength.