Applying quantitative immunology to the analysis of complex genetic diseases

每个人的免疫反应各不相同。对一些人来说，外来挑战引发的反应很弱，导致终生难以感染。对另一些人来说，这种反应更强，产生出色的免疫力，但也有可能对自身物质和自身免疫性疾病产生过度反应。我们有一个新的理论，可以测量我们免疫系统的健康状况，我们的目标是应用它来理解许多不同形式的人类免疫疾病的起源。

The immune response of each individual varies. For some, the response invoked by foreign challenge is weak, leading to a lifetime of difficulty with infection. For others, the response is stronger, yielding excellent immunity, but opening the potential for overactive responses to self-material and autoimmune disease. We have a new theory for how the health of our immune system can be measured and we aim to apply it to understand the genesis of the many different forms of human immune diseases.