Assessing the biogeography of the ocular microbiota and the impact of antibiotic prophylaxis
Assessing the biogeography of the ocular microbiota and the impact of antibiotic prophylaxis
批准号:
nhmrc : 1112537
负责人:
金额:
$21.61万
依托单位国家:
澳大利亚
项目类别:
Early Career Fellowships
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 2019-12-31
中文摘要
利用DNA测序,最近的研究已经确定了眼睛上的不同细菌群落,曾经被认为是稀少的微生物种群。这个项目将确定眼睛的驻留细菌是什么,以及这些细菌驻留在眼睛的什么地方。此外,白内障手术后,一些人会出现干眼问题。该项目将调查抗生素治疗是否会扰乱眼睛上的微生物群落,从而导致干眼症的发生。抗生素治疗是预防感染所必需的。
英文摘要
Using DNA sequencing, recent studies have identified a diverse community of bacteria on the eye, once believed to be sparsely populated by microbes. This project will identify what is the resident bacteria of the eye and where these bacteria reside on the eye. Also, after cataract surgery some individuals experience dry eye problems. This project will investigate if antibiotic therapy, necessary to prevent infection, disrupts the microbial communities on the eye leading to development of dry eye
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