Cancer cachexia therapeutics
Cancer cachexia therapeutics
批准号:
nhmrc : 1117541
负责人:
A/Pr Hamsa Puthalakath
金额:
$42.65万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Development Grants
财政年份:
2017
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2017-01-01 至 2018-12-31
中文摘要
我们已经发现了一种单一的肿瘤因子,它会导致癌症恶病质,这是恶性肿瘤最严重的并发症之一,目前还没有有效的治疗方法。我们已经开发出抗体,可以在临床前模型中有效地阻断这种情况,并已生产出这种抗体的人类/人源化版本。这个应用程序是为了描述这些人类抗体的特征,以便我们进行临床试验。
英文摘要
We have discovered a single tumour factor which causes cancer cachexia, a wasting condition that is one of the worst complications of malignancy, for which there is no current effective treatment. We have developed antibodies which effectively block this condition in preclinical models and have produced human/humanised version of this. This application is to characterise these human antibodies to allow us proceed to clinical trials.
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会议论文
Cancer cachexia therapeutics
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批准号:nhmrc : GNT1117541
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项目类别:Development Grants
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资助金额:$62.67万
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财政年份:2017
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负责人:A/Pr Hamsa Puthalakath
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依托单位:
Developing a new treatment method to prevent lymphopenia associated with sepsis
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批准号:nhmrc : GNT1085328
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项目类别:Project Grants
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资助金额:$42.25万
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财政年份:2015
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负责人:A/Pr Hamsa Puthalakath
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依托单位:
Developing a new treatment method to prevent lymphopenia associated with sepsis
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批准号:nhmrc : 1085328
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项目类别:Project Grants
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资助金额:$29.07万
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财政年份:2015
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负责人:A/Pr Hamsa Puthalakath
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依托单位:
DETERMINING THE ROLE OF ER STRESS INDUCED APOPTOSIS IN THYMIC NEGATIVE SELECTION
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批准号:nhmrc : 487311
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项目类别:NHMRC Project Grants
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资助金额:$37.22万
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财政年份:2008
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负责人:A/Pr Hamsa Puthalakath
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依托单位:
海外基金