Developing a new treatment method to prevent lymphopenia associated with sepsis

开发一种新的治疗方法来预防脓毒症相关的淋巴细胞减少症

• 批准号: nhmrc : 1085328
• 负责人: A/Pr Hamsa Puthalakath
• 金额: $ 29.07万
• 依托单位: La Trobe University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/developing-new-treatment-associated-sepsis/519075
• 关键词: Developing; new; treatment; method; prevent

Sepsis or blood poisoning kills more people than breast cancer, prostate cancer and HIV/AIDS combined. It has a huge economic burden, yet there is no proper diagnostics markers or treatment. One of the main reasons for sepsis-mediated mortality is lack of functioning immune system patients. We have been able to elucidate the molecular mechanism of sepsis-mediated immune cell death and through this project, we aim to develop diagnostics and therapy for treating sepsis-mediated immune suppression.

败血症或血液中毒导致的死亡人数超过了乳腺癌、前列腺癌和艾滋病毒/艾滋病的总和。它有巨大的经济负担，但没有适当的诊断标记或治疗方法。败血症导致死亡的主要原因之一是患者缺乏功能正常的免疫系统。我们已经能够阐明败血症介导的免疫细胞死亡的分子机制，通过这个项目，我们的目标是开发治疗败血症介导的免疫抑制的诊断和治疗方法。