Regulation of Megakaryocyte and Platelet Survival in Malignancy

在这项资助中，我们将研究在正常情况下和疾病期间血小板是如何产生的。血小板是一种血细胞，当我们被割伤时，它可以阻止我们流血。当血小板积聚过多时，血栓形成的风险就会增加。该项目资助将帮助我们了解血小板数量如何在某些血癌和卵巢癌的反应中膨胀，以及控制血小板和产生血小板的细胞死亡的机制。

In this grant we will investigate how blood cells called platelets are produced in normal conditions and during disease. Platelets are blood cells that stop us from bleeding when we get a cut. When too many platelets accumulate, there is an increased risk of blood clots forming. This project grant will help us learn how platelet numbers swell in response to some blood and ovarian cancers, and the mechanisms that control cell death in platelets and the cells that produce them.