Spatiotemporal interaction of saccades and visual motion processing

我们每秒进行几次称为扫视的快速眼球运动。快速眼球运动对扫描周围环境和提高视觉处理的敏感度很有用。尽管眼跳运动的频率及其对视觉输入的影响，我们通常认为世界是相当稳定的。也就是说，频繁改变视觉输入的眼球运动不会破坏我们处理视觉信息的能力。虽然这种稳定性被认为是神经机制的结果，这些神经机制将视觉输入与与每一次眼跳运动的指标相关的运动信号结合在一起。要了解这些机制是如何工作的，这项建议中描述的研究将专注于需要眼跳运动的任务中的视觉感知。我们的实验室将使用行为实验来确定受试者在进行眼跳运动时是如何处理视觉信息的。尤其是，我们将询问眼跳如何影响视觉处理的准确性和精确度，以及视觉处理如何影响眼跳运动的准确性。这些行为研究的结果将与监测参与眼动和视觉感知的神经元活动的电生理学研究结合起来。通过将知觉和电生理学研究结合起来，我们将加深对神经元事件和心理事件之间关系的理解，这对于理解大脑正常工作时的功能以及不正常时到底出了什么问题将是重要的。

We make rapid eye movements called saccades several times per second.  Saccades are useful for scanning one's surroundings and for improving the sensitivity of visual processing.  Despite the frequency of saccadic eye movements and their effects on the visual input, we generally perceive the world to be quite stable.  That is, the eye movements that frequently alter the visual input do not disrupt our ability to process visual information.  This stability is thought to be the result of neural mechanisms that combine visual input with motor signals related to the metrics of each saccadic eye movement.  To understand how these mechanisms work, the research described in this proposal will focus on visual perception during tasks that require saccadic eye movements.     Our laboratory will use behavioural experiments to determine how subjects process visual information around the time that they make a saccadic eye movement.  In particular, we will ask how the saccade affects the accuracy and precision of visual processing, and how visual processing affects the accuracy of saccadic eye movements.  The results from these behavioural studies will be combined with electrophysiological studies that monitor the activity of neurons that are involved in eye movements and visual perception.  By combining perceptual and electrophysiological studies, we will deepen our understanding of the relationship between neuronal events and mental events, which will be important in understanding how the brain functions when it works properly and exactly what goes wrong when it does not.