The relationship between osteoporosis and diabetes: exploring the bone-metabolism interface

骨质疏松症和糖尿病是影响许多澳大利亚人的两种常见疾病。糖尿病患者发生骨折的风险增加，但导致骨折风险增加的潜在机制尚不清楚。我们假设胰岛素水平升高（如2型糖尿病）会导致骨重塑发生变化，并将探索导致骨折风险增加的因素，并研究治疗方法如何降低骨折率。

Osteoporosis and diabetes are two common conditions that affect many Australians. Diabetes patients have an increased risk of fractures, however the underlying mechanisms for this increased fracture risk is unknown. We hypothesise that there are changes in the bone remodelling as a result of increased insulin levels (as seen in type 2 diabetes) and will explore the factors that contribute to the increased fracture risk and examine how treatments can reduce fracture rates.