The role of glutathione transferase P1 in regulating allergic airways disease
The role of glutathione transferase P1 in regulating allergic airways disease
批准号:
nhmrc : 471401
负责人:
Dr Dianne Webb
金额:
$29.13万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2008
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2008-01-01 至 2011-12-31
中文摘要
最近的研究表明,一种名为谷胱甘肽转移酶(GSTP)1的酶中的单个氨基酸变化可以防止患哮喘的可能性。这种酶存在于呼吸道细胞中,可以解毒污染物和香烟烟雾中的有害化学物质。我们研究的目的是了解GSTP1如何防止哮喘的发展。
英文摘要
Recent studies have shown that a single amino acid change in an enzyme called glutathione tranferase Pi (GSTP)1 protects against the likelihood of developing asthma. This enzyme is found in the cells that line the airways and detoxifies harmful chemicals such as those found in pollutants and cigarette smoke. The aim of our study is to understand how GSTP1 protects against the development of asthma.
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Characterisation of the signalling pathways utilised by IL-13 independently of IL-4R chain to mediate aspects of allerg
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批准号:nhmrc : 179841
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项目类别:Early Career Fellowships
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资助金额:$17.27万
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财政年份:2002
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负责人:Dr Dianne Webb
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依托单位:
海外基金