The role of Interferon-regulatory Factors in the host defense against bacterial infection
The role of Interferon-regulatory Factors in the host defense against bacterial infection
批准号:
nhmrc : GNT1091544
负责人:
Dr Si Ming Man
金额:
$33.43万
依托单位国家:
澳大利亚
项目类别:
Early Career Fellowships
财政年份:
2015
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2015-01-01 至 --
中文摘要
I型干扰素用于治疗病毒感染。然而,I型干扰素治疗细菌感染的潜力尚不清楚,因为我们不完全了解它们在细菌感染宿主中的功能作用和调节。我的建议旨在研究一个调节蛋白家族的作用,被称为干扰素调节因子,在宿主防御食源性细菌。
英文摘要
Type I interferons are used in the treatment of viral infection. However, the therapeutic potential of type I interferons for the treatment of bacterial infection is not known because we do not fully understand their functional roles and regulation in hosts infected with bacteria. My proposal aims to investigate the role of one family of regulatory proteins, known as interferon-regulatory factors, in the host defense against foodborne bacteria.
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会议论文
Molecular mechanisms of inflammasome activation
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批准号:nhmrc : GNT1162025
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项目类别:Career Development Fellowships
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资助金额:$43.7万
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财政年份:2019
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负责人:Dr Si Ming Man
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依托单位:
The role of DNA sensing in the pathogenesis of colorectal cancer
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批准号:nhmrc : GNT1146864
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项目类别:Project Grants
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资助金额:$62.5万
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财政年份:2018
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负责人:Dr Si Ming Man
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依托单位:
Type I interferon signalling in bacterial infection
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批准号:nhmrc : GNT1141504
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项目类别:Project Grants
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资助金额:$73.83万
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财政年份:2018
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负责人:Dr Si Ming Man
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依托单位:
国内基金
海外基金
系统性探索不同N-glycan修饰对Interferonβ活性和稳定性影响
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批准号:21877063
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项目类别:面上项目
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资助金额:61.4万元
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批准年份:2018
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负责人:王鹏
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依托单位:
糖药物蛋白Interferonβ N-glycan的均一、人源化改造
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批准号:81102361
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项目类别:青年科学基金项目
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资助金额:25.0万元
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批准年份:2011
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负责人:程剑松
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依托单位: