The Role of Snoring Vibrations in the Pathogenesis of Early Carotid Artery Atherosclerosis

习惯性打鼾症在成年人中是一个非常普遍的问题，患病率在20%-40%之间。现在越来越多的人认识到打鼾症可能是中风发病的一个独立的危险因素。在这项提案中，我们将探索一种假设，即慢性鼾症将压力波通过颈部组织传递到颈动脉，这可能会损害动脉壁，并随后导致中风。这可能会导致治疗习惯性打鼾症的新策略。

Habitual snoring is a very common problem in the adult population, with a prevalence of between 20-40%. Increasingly it is now recognised that snoring may be an independent risk factor for the development of stroke. In this proposal, we will explore the hypothesis that chronic snoring transmits a pressure wave through the tissues of the neck to the carotid artery which may damage the artery wall and subsequently lead to stroke. This may lead to new strategies to treat habitual snoring.