RP105 is a new innate immune receptor for Mycobacterium tuberculosis

结核病是一项重大的全球健康威胁，每年造成170万人死亡。这项研究将描述导致结核病的细菌与一种新的免疫传感器之间的相互作用。我们发现这种传感器参与了结核病的控制，这个项目将确定它如何有助于免疫防御感染。这些知识将有助于改善患者管理，开发有效的疫苗和更好的治疗这种毁灭性疾病的方法。

Tuberculosis (TB) is a major global health threat that causes 1.7 million deaths every year. This study will characterise the interactions between the bacteria that cause TB and a new immune sensor. We found that this sensor is involved in controlling TB and this project will determine how it contributes to the immune defence against the infection. Such knowledge will help improve patient management and develop an effective vaccine and better treatments for this devastating disease.