Solving the causes of and development of new therapies for ankylosing spondylitis and related diseases

强直性脊柱炎(AS)是一种高度可遗传的常见关节炎形式，主要影响脊柱和骨盆，是全球第二大最常见的关节炎形式(约0.55%)。在这项奖学金中，我将通过对其遗传和环境触发因素的研究，通过增加对其基本原因的了解，来扩展我的世界领先的AS研究计划，并由此开发出治疗这种疾病和相关疾病(如牛皮癣和炎症性肠病)的新疗法。

Ankylosing spondylitis (AS) is a highly heritable and common form of arthritis affecting primarily the spine and pelvis, and is the 2nd most common form of arthritis worldwide (~0.55%). In this fellowship I will extend my world-leading program of AS research by increasing understanding of its basic causes through research into its genetic and environmental triggers, and from this develop new treatments for this and related diseases such as psoriasis and inflammatory bowel disease.