课题基金 / 基金详情

Gas chromatograph mass spectrometer

Gas chromatograph mass spectrometer
气相色谱质谱仪
批准号:
375398-2009
负责人:
Wykes, Linda
金额:
$9.84万
依托单位:
依托单位国家:
加拿大
项目类别:
Research Tools and Instruments - Category 1 (<$150,000)
财政年份:
2008
资助国家:
加拿大
项目状态:
已结题
起止时间:
2008-01-01 至 2009-12-31

项目摘要

项目成果

Wykes, Linda的其他基金

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相关文献

中文摘要
翻译
靶向代谢组学或“通量组学”使用稳定同位素标记的多个示踪剂,是确定代谢对营养、发育状态和疾病变化的反应的有效方法。用稳定同位素标记的氨基酸示踪剂被注入动物和人类体内,以跟踪氨基酸在关键途径中的流动。然后将它们分配到不同的组织池中,确定特定蛋白质和其他产品的合成速度。这些具体和动态的衡量标准提供了比单独的集中度衡量更重要的信息,就像现金流和支出分析提供的财务信息比“手头现金”更有用一样。
英文摘要
TARGETED METABOLOMICS or "fluxomics" using multiple tracers labeled with stable isotopes is a powerful approach to determining metabolic responses to changes in nutrition, developmental state and disease. Amino acid tracers labeled with stable isotopes are infused in animals and humans to follow the flow of amino acids through critical pathways. Then their allocation into different tissue pools, the rates of synthesis of specific proteins and other products are determined. These specific and dynamic measures provide more important information than concentration measurements alone in much the same way that analysis of cash flow and expenditures provide more useful financial information than "cash-on-hand."
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Protein and amino acid metabolism in malnutrition and metabolic stress
  • 批准号:
    183710-2009
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $3.86万
  • 财政年份:
    2014
  • 负责人:
    Wykes, Linda
  • 依托单位:
Protein and amino acid metabolism in malnutrition and metabolic stress
  • 批准号:
    380302-2009
  • 项目类别:
    Discovery Grants Program - Accelerator Supplements
  • 资助金额:
    $2.91万
  • 财政年份:
    2012
  • 负责人:
    Wykes, Linda
  • 依托单位:
Protein and amino acid metabolism in malnutrition and metabolic stress
  • 批准号:
    183710-2009
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $3.86万
  • 财政年份:
    2012
  • 负责人:
    Wykes, Linda
  • 依托单位:
Protein and amino acid metabolism in malnutrition and metabolic stress
  • 批准号:
    183710-2009
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $3.86万
  • 财政年份:
    2011
  • 负责人:
    Wykes, Linda
  • 依托单位:
海外基金