Targeting phosphoinositide metabolism in Leishmania
Targeting phosphoinositide metabolism in Leishmania
批准号:
nhmrc : 1138863
负责人:
Prof Malcolm Mcconville
金额:
$67.0万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-01-01 至 2021-12-31
中文摘要
目前迫切需要开发新的药物来治疗人类利什曼病,这是一种在全世界数百万人中导致衰弱和危及生命的疾病。这个项目将研究是否有可能开发新一代药物,靶向这些寄生虫中的一个重要信号通路,我们已经证明这是毒力所必需的
英文摘要
There is an urgent need to develop new drugs to treat human leishmaniasis, a disease that causes debilitating and life-threatening diseases in millions of people worldwide. This project will investigate whether it is possible to develop a new generation of drugs that target an important signaling pathway in these parasites that we have shown to be essential for virulence
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会议论文
Targeting carbohydrate metabolism in Leishmania
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批准号:nhmrc : 1100000
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项目类别:Project Grants
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资助金额:$58.77万
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财政年份:2016
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负责人:Prof Malcolm Mcconville
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依托单位:
Identifying drug targets in microbial pathogens using metabolomics
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批准号:nhmrc : 1059530
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项目类别:Research Fellowships
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资助金额:$50.9万
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财政年份:2014
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负责人:Prof Malcolm Mcconville
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依托单位:
Targeting Toxoplasma gondii latent stages responsible for chronic disease
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批准号:nhmrc : 1046587
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项目类别:Project Grants
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资助金额:$46.48万
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财政年份:2013
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负责人:Prof Malcolm Mcconville
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依托单位:
Uncoupled Research
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批准号:nhmrc : 566643
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项目类别:NHMRC Research Fellowships
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资助金额:$46.85万
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财政年份:2009
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负责人:Prof Malcolm Mcconville
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依托单位:
Evolution and targeting of polysaccharide biosynthesis in Leishmania parasites
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批准号:nhmrc : 566644
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项目类别:NHMRC Project Grants
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资助金额:$29.97万
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财政年份:2009
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负责人:Prof Malcolm Mcconville
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依托单位:
Polysaccharide biosynthesis as a new drug target in Leishmania parasites
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批准号:nhmrc : 400035
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项目类别:NHMRC Project Grants
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资助金额:$28.17万
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财政年份:2006
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负责人:Prof Malcolm Mcconville
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依托单位:
Uncoupled Research Fellowship
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批准号:nhmrc : 299903
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项目类别:NHMRC Research Fellowships
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资助金额:$42.59万
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财政年份:2004
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负责人:Prof Malcolm Mcconville
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依托单位:
Ongoing Uncoupled Research Fellowship
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批准号:nhmrc : 170218
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项目类别:NHMRC Research Fellowships
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资助金额:$22.2万
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财政年份:2001
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负责人:Prof Malcolm Mcconville
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依托单位:
Regulation of glycosylation pathways in parasitic protozoa
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批准号:nhmrc : 990269
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项目类别:NHMRC Project Grants
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资助金额:$64.67万
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财政年份:1999
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负责人:Prof Malcolm Mcconville
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依托单位:
国内基金
海外基金
Posphoinositide-dependent kinase-1在肿瘤细胞趋化运动和转移中的作用机制
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批准号:30772529
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项目类别:面上项目
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资助金额:29.0万元
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批准年份:2007
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负责人:张宁
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依托单位: