Targeting the Plasmodium falciparum Metalloaminopeptidases for Development of New Antimalarial Agents
Targeting the Plasmodium falciparum Metalloaminopeptidases for Development of New Antimalarial Agents
批准号:
nhmrc : 1063786
负责人:
Dr Sheena Mcgowan
金额:
$37.71万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2014
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2014-01-01 至 2016-12-31
中文摘要
每年将有1- 200万人死于疟疾。由于耐药性的蔓延,疟疾的预防和治疗变得越来越困难。迫切需要具有新作用方式的下一代抗疟药物。本项目将针对疟疾氨基肽酶药物靶点开发新的抗疟药物。
英文摘要
Each year 1-2 million people will die from malaria. The prevention and treatment of malaria is becoming increasingly difficult due to the spread of drug-resistance. There is an urgent need for next generation of antimalarials with new modes of action. This project will develop new antimalarial agents against the malarial aminopeptidase drug targets.
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会议论文
Anti-Malarial Agents Targeting Apical Membrane Antigen 1
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批准号:nhmrc : 1098884
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项目类别:Project Grants
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资助金额:$45.38万
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财政年份:2016
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负责人:Dr Sheena Mcgowan
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依托单位:
Development of Antimalarial Drug Leads Through Inhibition of Food Vacuole Falcipains
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批准号:nhmrc : 1062216
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项目类别:Project Grants
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资助金额:$43.29万
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财政年份:2014
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负责人:Dr Sheena Mcgowan
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依托单位:
A New Class of Anti-Malarial Agents Targetting Apical Membrane Antigen
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批准号:nhmrc : 1025150
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项目类别:Project Grants
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资助金额:$39.85万
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财政年份:2012
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负责人:Dr Sheena Mcgowan
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依托单位:
海外基金