Tracking Endogenous Presentation of MHC class-II-Restricted Viral Epitopes
Tracking Endogenous Presentation of MHC class-II-Restricted Viral Epitopes
追踪 MHC II 类限制性病毒表位的内源呈现
批准号：
nhmrc : 552501
负责人：
Dr Tania Crough
金额：
$11.03万
依托单位国家：
澳大利亚
项目类别：
Early Career Fellowships
财政年份：
2009
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2009-01-01 至 2012-12-31
中文摘要
翻译
CD4+ T细胞在控制病毒感染中发挥重要作用。来自病毒的蛋白质被免疫刺激细胞加工成小块，然后这些小块被显示在免疫刺激细胞的特殊分子上，供CD4+ T细胞识别和响应。该项目旨在建立免疫刺激细胞处理蛋白质并将其呈现给CD4+ T细胞的各种途径。
英文摘要
CD4+ T cells play an important role in controlling viral infections. Proteins from viruses are processed into small pieces by immune stimulating cells and these are then displayed on special molecules of the immune stimulating cells for the CD4+ T cells to recognise and respond to. This project aims to establish the various pathways by which the immune stimulating cells process the proteins and present them to the CD4+ T cells.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
海外基金
