Genetic and physiological basis of growth, survival and reproduction in Chinook salmon: applications for aquaculture

拟议研究的主要目的是开发和评估高性能和低性能奇努克鲑鱼品系，以便在加拿大西海岸的有机鲑鱼养殖业中直接或杂交使用。因此，菌株和杂交种不仅必须具有高生长和繁殖性能，还必须具有特殊的抗病能力，因为不可能使用治疗药物。我们将通过四大目标来实现我们的目标；1)在我们的工业合作伙伴（黄岛水产养殖有限公司）使用现有精选的奇努克鲑鱼高、低存活率系；2)评价已开发的性能遗传标记在YIAL选育品系和数量遗传育种试验子代中的状况；3)测定育种试验子代的生命阶段特定性能（如生存、生长等）；4)确定生产性能性状的遗传基础，估计性状间的遗传相关性。由于我们将使用无源集成应答器（PIT）标签技术跟踪来自100个家庭群体的单个后代，我们将能够确定对水产养殖有价值的特定性状的遗传能力以及可能提高品系性能的其他遗传参数。这项研究的商业营销潜力很大，无论是在加拿大国内还是出口。拟议的研究不仅将为学术伙伴提供与加拿大水产养殖业合作的机会，还将产生应用和基础科学、训练有素的学生和科学出版物。

The primary objective of the proposed research is to develop and evaluate high and low performance strains of Chinook salmon for direct or hybrid use in the Organic Salmon Aquaculture industry on the west coast of Canada. The strains and hybrids must therefore not only have high growth and reproductive performance, they must also have exceptional disease resistance, because theraputant use is not possible. We will address our objective with 4 broad goals; 1) use the existing selected high and low survival lines of Chinook salmon at our Industrial partner's (Yellow Island Aquaculture Ltd.; YIAL) facility to carry out a quantitative genetic breeding experiment, 2) evaluate the status of the previously-developed performance genetic markers in the YIAL selected lines as well as in the offspring from the quantitative genetic breeding experiment, 3) measure life-stage specific performance (e.g. survival, growth) in the offspring from the breeding experiment, and 4) determine the genetic basis of performance traits and estimate genetic correlations among traits. Since we will follow individual offspring from 100 family groups using Passive Integrated Transponder (PIT) tag technology, we will be able to determine the heritability for specific traits of value to aquaculture and other genetic parameters that may add performance to the lines. The potential for commercial marketing of this research is good, both within Canada and for export. The proposed research will not only provide an opportunity for the academic partners to collaborate with the Canadian aquaculture industry, it will generate applied and basic science, highly trained students and scientific publications.