Understanding how Hepatitis C Virus and Human Immunodeficiency Virus mediate viral entry; rational design of novel vaccines.
Understanding how Hepatitis C Virus and Human Immunodeficiency Virus mediate viral entry; rational design of novel vaccines.
批准号:
nhmrc : 1041897
负责人:
A/Pr Heidi Drummer
金额:
$56.1万
依托单位国家:
澳大利亚
项目类别:
Research Fellowships
财政年份:
2013
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2013-01-01 至 2018-12-31
中文摘要
丙型肝炎病毒(HCV)和人类免疫缺陷病毒(HIV)分别感染全球2亿和5000万人,并且没有预防性疫苗。这项研究概述的工作旨在了解这些病毒的主要表面蛋白的结构和功能,它们被免疫系统识别的能力,以及开发预防HCV的新型疫苗。
英文摘要
Hepatitis C virus (HCV) and Human immunodeficiency virus (HIV) infect 200 million and 50 million people world-wide, respectively, and there are no preventative vaccines. The work outlined in this fellowship seeks to understand the structure and function of the major surface proteins of these viruses, their ability to be recognised by the immune system and to develop a novel vaccine for the prevention of HCV.
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科研奖励(0)
会议论文
Novel HIV-1 glycoprotein vaccines with enhanced presentation of broad neutralization epitopes
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批准号:nhmrc : 1125822
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项目类别:Project Grants
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资助金额:$50.76万
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财政年份:2017
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负责人:A/Pr Heidi Drummer
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依托单位:
Novel HIV-1 glycoprotein vaccines with enhanced presentation of broad neutralization epitopes
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批准号:nhmrc : GNT1125822
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项目类别:Project Grants
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资助金额:$74.37万
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财政年份:2017
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负责人:A/Pr Heidi Drummer
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依托单位:
Developing a quadrivalent HCV vaccine
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批准号:nhmrc : 1126379
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项目类别:Project Grants
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资助金额:$44.62万
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财政年份:2017
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负责人:A/Pr Heidi Drummer
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依托单位:
Developing a quadrivalent HCV vaccine
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批准号:nhmrc : GNT1126379
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项目类别:Project Grants
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资助金额:$65.37万
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财政年份:2017
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负责人:A/Pr Heidi Drummer
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依托单位:
Profiling the specificity of the neutralizing antibody response in people who have long term protection from developing chronic HCV
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批准号:nhmrc : GNT1106581
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项目类别:Project Grants
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资助金额:$37.3万
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财政年份:2016
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负责人:A/Pr Heidi Drummer
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依托单位:
Profiling the specificity of the neutralizing antibody response in people who have long term protection from developing chronic HCV
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批准号:nhmrc : 1106581
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项目类别:Project Grants
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资助金额:$25.64万
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财政年份:2016
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负责人:A/Pr Heidi Drummer
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依托单位:
A universal prophylactic vaccine for Hepatitis C Virus
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批准号:nhmrc : 1080045
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项目类别:Project Grants
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资助金额:$42.9万
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财政年份:2015
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负责人:A/Pr Heidi Drummer
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依托单位:
Function and immunogenicity of the HIV-1 glycoproteins
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批准号:nhmrc : GNT1070890
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项目类别:Project Grants
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资助金额:$41.05万
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财政年份:2014
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负责人:A/Pr Heidi Drummer
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依托单位:
Studies on the activation and immunogenicity of the HIV-1 glycoproteins, gp120-gp41
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批准号:nhmrc : 1070890
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项目类别:Project Grants
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资助金额:$40.44万
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财政年份:2014
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负责人:A/Pr Heidi Drummer
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依托单位:
Viral entry and the development of vaccines.
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批准号:nhmrc : GNT1041897
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项目类别:Research Fellowships
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资助金额:$66.58万
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财政年份:2013
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负责人:A/Pr Heidi Drummer
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依托单位:
Roles of the hepatitis C virus glycoprotein E2 variable regions in virus entry, immunogenicity and immune evasion.
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批准号:nhmrc : 1020175
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项目类别:Project Grants
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资助金额:$45.53万
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财政年份:2012
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负责人:A/Pr Heidi Drummer
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依托单位:
Elucidating the activation mechanism of the HIV-1 envelope glycoproteins, gp120-gp41
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批准号:nhmrc : 1009809
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项目类别:NHMRC Project Grants
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资助金额:$42.47万
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财政年份:2011
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负责人:A/Pr Heidi Drummer
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依托单位:
Structural and functional role of HIV-1 gp41 terminal interactions in the membrane fusion mechanism
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批准号:nhmrc : 543125
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项目类别:NHMRC Project Grants
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资助金额:$35.32万
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财政年份:2009
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负责人:A/Pr Heidi Drummer
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依托单位:
Role of the hepatitis C virus glycoprotein E2 variable regions in viral entry and antibody mediated neutralization.
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批准号:nhmrc : 543113
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项目类别:NHMRC Project Grants
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资助金额:$36.17万
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财政年份:2009
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负责人:A/Pr Heidi Drummer
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依托单位:
Structure and function of the Hepatitis C Virus and Human Immunodeficiency Virus glycoproteins
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批准号:nhmrc : 433929
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项目类别:Career Development Fellowships
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资助金额:$31.5万
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财政年份:2008
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负责人:A/Pr Heidi Drummer
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依托单位:
Delineation of receptor-activated conformational signalling pathways in HIV-1 envelope glycoproteins
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批准号:nhmrc : 488204
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项目类别:NHMRC Project Grants
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资助金额:$55.64万
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财政年份:2008
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负责人:A/Pr Heidi Drummer
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依托单位:
Structure and function of the Hepatitis C Virus glycoproteins E1 and E2.
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批准号:nhmrc : 433913
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项目类别:NHMRC Project Grants
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资助金额:$35.6万
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财政年份:2007
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负责人:A/Pr Heidi Drummer
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依托单位:
Characterization of neutralizing antibody responses in HCV infected individuals.
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批准号:nhmrc : 381713
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项目类别:NHMRC Project Grants
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资助金额:$31.88万
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财政年份:2006
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负责人:A/Pr Heidi Drummer
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依托单位:
Receptor activated conformations of retroviral glycoproteins.
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批准号:nhmrc : 345413
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项目类别:NHMRC Project Grants
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资助金额:$32.61万
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财政年份:2005
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负责人:A/Pr Heidi Drummer
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依托单位:
Structure and function of Hepatitis C Virus glycoproteins
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批准号:nhmrc : 296200
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项目类别:NHMRC Project Grants
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资助金额:$32.06万
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财政年份:2004
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负责人:A/Pr Heidi Drummer
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依托单位:
海外基金