Understanding the role of CD4 T cells in viral infection: a means of improving anti-viral immunotherapy.

开发预防和治疗慢性感染的疗法是最优先的事项，因为它们会造成相当大的临床挑战和持续的卫生保健费用。努力改善慢性病毒感染的治疗，如由艾滋病毒、丙型肝炎病毒和人类巨细胞病毒引起的慢性病毒感染，需要更好地了解长期控制这些病毒所需的免疫反应。本研究将探讨CD4+ T细胞在控制慢性病毒感染中的作用。

Development of therapies to prevent and treat chronic infections is of the highest priority as they cause considerable clinical challenges and on-going health care costs. Efforts to improve treatment of chronic viral infections, such as those caused by HIV, hepatitis C virus and human cytomegalovirus, require a better understanding of the immune responses needed to control these viruses long-term. This proposal will investigate the role of CD4+ T cells in controlling chronic viral infection.