The unholy alliance between extracorporeal circuitry and transfusion medicine: characterising inflammation and injury

体外膜氧合（ECMO）是一种心脏/肺部机器，用氧气代替血液中的二氧化碳，使器官在感染或创伤后有机会休息。它在猪流感爆发时挽救了许多人的生命。血液穿过异物表面会引起炎症、细胞损伤和需要输血。本研究旨在确定ECMO的哪个部分引起损伤以及如何引起损伤。这将提高最严重的心脏和呼吸系统疾病的存活率。

Extra Corporeal Membrane Oxygenation (ECMO) is a heart/lung machine that replaces blood CO2 with oxygen, giving organs a chance to rest after injury due to infection or trauma. It saved many lives in the swine flu outbreak. Blood moving across foreign surfaces causes inflammation, cell injury and a need for transfusions. This study aims to identify which part of the ECMO causes injury and how. This will to improve survival rates of the most severe forms of cardiac and respiratory disease.