Identification and characterization of novel substrates of the mammalian target of rapamycin complex 1 (mTORC1).
Identification and characterization of novel substrates of the mammalian target of rapamycin complex 1 (mTORC1).
批准号:
241072
负责人:
Topisirovic Ivan
金额:
$21.86万
依托单位国家:
加拿大
项目类别:
Salary Programs
财政年份:
2011
资助国家:
加拿大
项目状态:
已结题
起止时间:
2011-09-01 至 2016-09-01
中文摘要
哺乳动物雷帕霉素靶蛋白复合物1(mTORC 1)的活性在以代谢和增殖异常为特征的人类疾病(例如糖尿病、癌症和心脏病)中经常失调。因此,调节活性的化合物
英文摘要
The activity of the mammalian target of rapamycin complex 1 (mTORC1) is frequently dysregulated in human diseases characterized by abnormal metabolism and proliferation such as diabetes, cancer and heart disease. Accordingly, compounds modulating the acti
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会议论文
The role of oncogenic hydride ion transfer complex (HTC) in metabolic plasticity, cancer progression and therapeutic responses.
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批准号:461526
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项目类别:Operating Grants
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资助金额:$64.09万
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财政年份:2022
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负责人:Topisirovic Ivan
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依托单位:
The role of CK2 in translational reprogramming in cancer
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批准号:433448
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资助金额:$78.02万
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财政年份:2020
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负责人:Topisirovic Ivan
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依托单位:
The role of epitranscriptome and translational dysregulation in cancer
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批准号:364391
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项目类别:Operating Grants
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资助金额:$0.0万
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财政年份:2017
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负责人:Topisirovic Ivan
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依托单位:
Investigating the role of eIF2ß in translation reprogramming in cancer
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批准号:342900
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项目类别:Operating Grants
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资助金额:$77.97万
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财政年份:2016
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负责人:Topisirovic Ivan
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依托单位:
Identification and characterization of novel substrates of the mammalian target of rapamaycin complex 1 (mTORC1).
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批准号:224753
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项目类别:Operating Grants
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资助金额:$41.92万
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财政年份:2011
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负责人:Topisirovic Ivan
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依托单位:
国内基金
海外基金
中国北方人群肺癌患者Cancer/Testis抗原表达谱绘制表位鉴定及功能性抗原特异性CTL制备研究
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批准号:81673007
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项目类别:面上项目
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资助金额:54.0万元
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批准年份:2016
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负责人:金时
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依托单位: