Efficient, stable, and easily accessible catalysts for hydrogenation of esters

在有机化学中，羧酸酯还原是一种常见的反应。现有的经典技术是危险的，而且伴随着化学废物的过度形成。我们实验室的新型过渡金属催化剂有助于在氢气中提供醇的绿色酯还原过程，基本上没有化学废物。我们团队目前的研究目标是为学术和工业化学家提供负担得起、易于操作、易于获得和高效的均相催化剂，用于羰基化合物的加氢。我们的新型催化剂将引起加拿大和美国的香料和香料制造商以及特种和精细化合物生产商的兴趣。该提案要求为一个12个月的项目提供资金，以生产完全适用于工业环境的改进的催化系统和运行数据。

Reduction of carboxylic esters is a common reaction in organic chemistry. Existing classical techniques are hazardous and they are accompanied by excessive formation of chemical waste. New transition metal catalysts from our laboratory facilitate a 'green' ester reduction process affording alcohols under hydrogen gas with essentially no chemical waste. The objective of current research in our group is to offer academic and industrial chemists affordable, easy to handle, readily available and efficient homogeneous catalysts for hydrogenation of carbonyl compounds. Our new catalysts will be of interest to Canadian and American flavour and fragrances manufacturers and producers of specialty and fine chemical compounds. This proposal request funding for a 12 month project to produce improved catalytic systems and operational data fully applicable to industrial settings.