Gel documentation system for multi-user facility

所要求的凝胶文件系统将满足多伦多大学细胞和系统生物学系的研究人员、他们的学生和博士后研究员的需求。该系的研究涵盖了生命科学的一系列领域，包括细胞和发育生物学、遗传学和生理学。凝胶文档是分子生物学实验室中的关键诊断工具。建议的凝胶记录仪器将用于记录和分析许多实验方法和程序的结果，这些方法和程序涉及生物大分子DNA、RNA和蛋白质。它需要可视化和评价DNA和RNA分离、DNA酶切、聚合酶链式反应、体外转录、蛋白质表达、蛋白质相互作用研究、突变基因和重组基因构建的产物。这些实验室程序产生了我们用来理解分子网络的工具，基因及其产物在其中运作，以及这些网络如何决定细胞和组织的结构和功能。研究人员使用各种模式生物来探索调节细胞和组织发育和功能的分子过程。在这些实验室工作的许多受训人员每天需要使用凝胶文档系统几次来记录和分析他们的实验结果。因此，高效和高质量的凝胶文档系统是最先进的研究和培训环境的重要组成部分。

The requested Gel documentation System will serve the needs of researchers, their students and postdoctoral fellows in the Department of Cell and Systems Biology at the University of Toronto. Research in the department encompasses a range of fields in the life sciences including cell and developmental biology, genetics, and physiology. Gel documentation is a critical diagnostic tool in a molecular biology laboratory. The proposed gel documentation instrument will be used to record and analyze the results of many experimental approaches and procedures that involve the biological macromolecules DNA, RNA, and protein. It is required to visualize and evaluate the products of DNA and RNA isolation, DNA digests, PCR, in vitro transcription, protein expression, protein interaction studies, mutagenized genes, and recombinant gene construction. These laboratory procedures generate the tools that we use to understand the molecular networks, in which genes and their products operate, and how these networks determine the structure and function of cells and tissues. The researchers use various model organisms to explore the molecular processes that regulate development and function of cells and tissues. The many trainees working in these labs need to use a gel documentation system several times per day to record and analyze their experimental results. Thus, an efficient and high-quality gel documentation system is an essential component of a state-of-the-art research and training environment.