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Role of Gfi1 as a modulator of the ATM/DNA-PK DNA damage response pathway

Role of Gfi1 as a modulator of the ATM/DNA-PK DNA damage response pathway
Gfi1 作为 ATM/DNA-PK DNA 损伤反应途径调节剂的作用
批准号：
265650
负责人：
Moroy Tarik
金额：
$50.0万
依托单位：
Institut de recherches cliniques de Montral
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2012
资助国家：
加拿大
项目状态：
已结题
起止时间：
2012-09-01 至 2017-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=265650&lang=en
关键词：
Dna Damage Response Leukemia Programmed Cell Death Signal Transduction Transcription Factors Transgenic And Knockout Mice

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中文摘要
翻译
当细胞受到伽马射线照射或某些化疗药物时，染色体，特别是染色体内的DNA会受到破坏。因此，细胞通过停止细胞分裂来修复损伤来做出反应。如果维修
英文摘要
When cells are subjected to gamma irradiation or certain chemotherapeutic drugs, the chromosomes and in particular the DNA within the chromosomes are damaged. As a consequence, the cells respond by stopping cell division to repair the damage. If the repai
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