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Functional characterization of the Gct1 gene product in a mouse ovarian tumour model: genetics, biology and translation

Functional characterization of the Gct1 gene product in a mouse ovarian tumour model: genetics, biology and translation
小鼠卵巢肿瘤模型中 Gct1 基因产物的功能表征:遗传学、生物学和翻译
批准号:
277283
负责人:
Smith Kerri N
金额:
$3.82万
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2012
资助国家:
加拿大
项目状态:
已结题
起止时间:
2012-10-01 至 2015-10-01

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中文摘要
翻译
我们对癌症易感基因的理解已经通过对特定癌症的遗传家族的研究得到了极大的加强。癌症易感性基因在小儿病因学中起着特别重要的作用
英文摘要
Our understanding of cancer susceptibility genes has been greatly enhanced through the study of families that show genetic heritability for specific cancers. Genes for cancer susceptibility play a particularly important role in the etiology of pediatric
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会议论文
Genetic Polymorphisms Associated with Juvenile-Onset Granulosa Cell Tumour Susceptibility in SWR Mice
Identification of Gct1 using Next Generation sequencing and functional candidate testing in vivo
A candidate gene short list for a granulosa cell tumour susceptibility gene (Gct1) in a spontaneous mouse model of early-onset tumourigenesis
Positional cloning of the Gct1 granulosa cell tumour susceptibility locus in SWR/Bm inbred mice.
  • 批准号:
    200160
  • 项目类别:
    Studentship Programs
  • 资助金额:
    $1.27万
  • 财政年份:
    2010
  • 负责人:
    Smith Kerri N
  • 依托单位:
海外基金