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Genomic regulation of hippocampal postnatal development and neuron activity by H2A histone variants and their post-translational modifications is influenced by early maternal care

Genomic regulation of hippocampal postnatal development and neuron activity by H2A histone variants and their post-translational modifications is influenced by early maternal care
H2A 组蛋白变体及其翻译后修饰对海马产后发育和神经元活动的基因组调控受到早期孕产妇护理的影响
批准号：
284234
负责人：
Thambirajah Anita A
金额：
$3.28万
依托单位：
Douglas Mental Health University Institute (Montreal, QC)
依托单位国家：
加拿大
项目类别：
Fellowship Programs
财政年份：
2013
资助国家：
加拿大
项目状态：
已结题
起止时间：
2013-02-01 至 2014-02-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=284234&lang=en
关键词：
Chip-Sequencing Chromatin Epigenetics Hippocampus Histone Variants Immunohistochemistry Neurodevelopment Qrt-Pcr Stranded Rna-Sequencing Western Blotting

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中文摘要
翻译
胎儿和幼儿的发育以大脑结构和组织的深刻变化为标志。随着孩子的成熟，大脑经历了戏剧性的增长，因为神经元形成新的连接并消除多余的连接。这种脑生理变化，
英文摘要
Fetal and early child development is marked by profound changes in brain structure and organization. As a child matures, the brain undergoes dramatic growth as neurons form new connections and eliminate superfluous ones. Such alterations in brain physiolo
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Variations in heterotypic H2A histone variants characterize post-natal neural developmental in the rat hippocampus
  • 批准号：
    253692
  • 项目类别：
  • 资助金额：
    $0.07万
  • 财政年份：
    2012
  • 负责人：
    Thambirajah Anita A
  • 依托单位：
    McGill University
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