Development of a thermal cycling unit for DNA amplification using polymerase chain reaction in a microfluidic platform

UFluidx致力于为广泛的应用开发新型的芯片实验室(LOC)仪器。UFluidix目前的项目之一是开发一种手持LOC仪器并将其商业化，该仪器利用微流控技术在农场检测猪繁殖与呼吸综合征(PRRS)疾病。PRRS仍然是一种无法治愈的传染病，每年都会给养殖业带来巨大的经济和社会压力。有希望的解决方案之一是通过遏制病毒进行有效预防，这需要一种便携式农场诊断工具来区分疾病猪和健康猪。聚合酶链式反应(PCR)是一种强大的DNA扩增技术，已被证明在疾病诊断中取得了成功。因此，一种集成微流控通道实现聚合酶链式反应的LOC仪器

uFluidix is committed to developing novel Lab-on-a-Chip (LOC) instruments for a wide range of applications. One of uFluidix's current projects is to develop and commercialize a hand-held LOC instrument that utilizes microfluidic technology for on-farm detection of Porcine Reproductive and Respiratory Syndrome (PRRS) disease. PRRS remains an incurable infectious disease and causes significant economic and social stresses to the farm industry every year. One of the promising solutions is effective prevention through containment of the virus which requires a portable on-farm diagnostics tool to differentiate sick from healthy pigs. Polymerase chain reaction (PCR) which is a powerful technique for DNA amplification has proven to be successful for disease diagnosis. Therefore a LOC instrument integrated with microfluidic channels for realizing PCR