Photonic sensing systems bases on a Lab-on-a-Fiber concept for specific cyanobacteria detection in water

我们的研究项目将集中在新型液相光纤传感（FOS）设备和仪器系统的设计，制造和表征，用于识别，检测和监测选定的生物物质。还将研究将光子检测机制和能力集成到本地和远程生物传感器系统中。通过类比芯片实验室的概念，我们将开发基于我们的光纤实验室（LOF）概念的光子传感设备和传感子系统，目前正在我们的各个实验室进行初步探索。在这种方法中，所有的传感、传输和解码功能都将基于光纤本身，而光纤（或基于光纤的设备）的传感部分的选定外表面或内表面将通过选定的细菌特异性纳米涂层来功能化。我们的FOS系统的目标应用是实时检测危险的微囊藻毒素生产蓝藻。我们希望实现近距离传感与手持设备和远程监测蓝藻使用检测系统部署在室外水库。将在光纤和光纤设备的特定位置开发和涂覆有源涂层和膜，以构建传感器点探针和传感器阵列。该研究还将涉及研究，制造，测试和优化新的传感光纤和光纤器件结构;新的解码和仪器架构;传感器阵列的新多路复用拓扑结构;以及单光子传感器和多光子传感器的新校准和被测量重建程序。我们基于LOF提出的（最近证实可行的）解决方案

Our research project will concentrate on the design, fabrication and characterization of novel liquid-phase fiber-optic sensing (FOS) devices and instrumentation systems for identification, detection and monitoring of selected biological substances. Integration of photonic detection mechanisms and capabilities into local and remote biosensor systems will also be studied. By analogy to the lab-on-a-chip concept, we will develop photonic sensing devices and sensing subsystems based on our lab-on-a-fiber (LOF) concept currently under initial exploration in our individual laboratories. In this approach, all sensing, transmission and decoding functions will be based on the optical fiber itself, while selected outside or inside surfaces of the sensing part of the fiber (or fiber-based device) will be functionalized by selected bacteria-specific nano-coatings. The target application for our FOS systems is real-time detection of dangerous micro-cystin producing cyanobacteria. We expect to achieve both close-range sensing with hand-held devices and remote monitoring of cyanobacteria using detection systems deployed in outdoor water reservoirs. Active phages and membranes will be developed and coated at specific locations on optical fibers and fiber devices to build sensor point probes and sensor arrays. The research will also involve studying, fabricating, testing and optimizing new sensing fiber and fiber device structures; new decoding and instrumentation architectures; new multiplexing topologies for sensor arrays; and new calibration and measurand reconstruction procedures for single and multiple photonic sensors. Our proposed (and recently confirmed as feasible) solution based on the LOF