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Exploring the functional, structural, and behavioral determinants of repeated early-life stress exposure and the regulatory role of the endocannabinoid system

Exploring the functional, structural, and behavioral determinants of repeated early-life stress exposure and the regulatory role of the endocannabinoid system
探索生命早期反复压力暴露的功能、结构和行为决定因素以及内源性大麻素系统的调节作用
批准号：
308824
负责人：
McLaughlin Ryan J
金额：
$0.36万
依托单位：
Douglas Mental Health University Institute (Montreal, QC)
依托单位国家：
加拿大
项目类别：
Fellowship Programs
财政年份：
2013
资助国家：
加拿大
项目状态：
已结题
起止时间：
2013-11-01 至 2014-11-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=308824&lang=en
关键词：
Amygdala Dendritic Morphology Early Life Stress Endocannabinoid Signaling Fear Learning Hypothalamic-Pituitary-Adrenal Axis Immunohistochemistry In Situ Hybridization In Vitro Electrophysiology Prefrontal Cortex

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中文摘要
翻译
在生命的最初几周暴露于压力下会对大脑发育以及我们如何处理未来的压力遭遇产生深远的影响。在啮齿类动物中，早期生活的压力源，如长期与母亲分离，
英文摘要
Exposure to stress during the first few weeks of life can have profound effects on brain development and how we process future stressful encounters. In rodents, early-life stressors such as prolonged separation from the mother produces exaggerated release
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Exploring the functional, structural, and behavioral determinants of repeated early-life stress exposure and the regulatory role of the endocannabinoid system
Prefrontocortical Cannabinoid Receptor Upregulation is Adaptive in an Animal Model of Depression
  • 批准号：
    184550
  • 项目类别：
    Studentship Programs
  • 资助金额：
    $7.65万
  • 财政年份：
    2008
  • 负责人：
    McLaughlin Ryan J
  • 依托单位：
    University of British Columbia
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