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Microtubule dynamics and age-related aneuploidy in mammalian oocytes

Microtubule dynamics and age-related aneuploidy in mammalian oocytes
哺乳动物卵母细胞的微管动力学和年龄相关的非整倍性
批准号:
321378
负责人:
Fitzharris Greg
金额:
$43.89万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2015
资助国家:
加拿大
项目状态:
已结题
起止时间:
2015-03-01 至 2020-03-01

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中文摘要
翻译
在受精过程中,精子和卵子的融合产生了一个新的个体,每一个都为后代贡献了一半的遗传物质(染色体)。然而,由于人们知之甚少的原因,卵子的发育并没有
英文摘要
At fertilisation a new individual is created by the fusion of the sperm and the egg, each of which contributes half of the genetic material (chromosomes) for the offspring. However, for reasons that are very poorly understood, the development of the egg i
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What is the underlying cause of mosaic aneuploidy in the preimplantation embryo?
The role of the kinetochore in age-related oocyte aneuploidy
What is the cause of chromosome segregation error in the mammalian preimplantation embryo?
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