课题基金 / 基金详情

Articular Cartilage Reconstruction

Articular Cartilage Reconstruction
关节软骨重建
批准号:
462232-2014
负责人:
Amsden, Brian
金额:
$3.19万
依托单位:
依托单位国家:
加拿大
项目类别:
Collaborative Health Research Projects
财政年份:
2015
资助国家:
加拿大
项目状态:
已结题
起止时间:
2015-01-01 至 2016-12-31

项目摘要

项目成果

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中文摘要
翻译
膝盖骨表面组织的损伤,以及提供平滑关节运动的组织,最终会 形成裂纹和缺陷。这些裂缝和缺陷导致与关节炎相关的疼痛,称为 骨关节炎我们计划开发一种治疗方法,在这些缺陷达到这个阶段之前, 其中关节运动受到损害并且患者经历与这种不可逆损伤相关的疼痛。的 治疗方法包括外科医生将一种聚合物水溶液注射到缺损处, 从脂肪。聚合物+细胞溶液在组织中固化,填充空间,干细胞诱导损伤愈合 组织.
英文摘要
Damage to the tissue that lines the surface of the bones of the knees, and that provide smooth joint motion, can ultimately progress to form cracks and defects. These cracks and defects result in the pain associated with arthritis, and is called osteoarthritis. We plan on developing a treatment method wherein we will fill these defects before they can reach the stage where the joint motion is compromised and the patient experiences the pain associated with this irreversible damage. The treatment involves a surgeon injecting into the defect a polymer in water solution that also contains stem cells harvested from fat. The polymer + cells solution cures in the tissue, filling the space and the stem cells induce healing of the damaged tissue.
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Aliphatic polycarbonates: building blocks for new biodegradable biomaterials
  • 批准号:
    RGPIN-2020-05598
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $4.66万
  • 财政年份:
    2022
  • 负责人:
    Amsden, Brian
  • 依托单位:
Cell culture suite
  • 批准号:
    RTI-2022-00275
  • 项目类别:
    Research Tools and Instruments
  • 资助金额:
    $9.63万
  • 财政年份:
    2021
  • 负责人:
    Amsden, Brian
  • 依托单位:
Aliphatic polycarbonates: building blocks for new biodegradable biomaterials
  • 批准号:
    RGPIN-2020-05598
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $4.66万
  • 财政年份:
    2021
  • 负责人:
    Amsden, Brian
  • 依托单位:
CONNECT! NSERC CREATE Program In Soft Connective Tissue Regeneration/Therapy
  • 批准号:
    465675-2015
  • 项目类别:
    Collaborative Research and Training Experience
  • 资助金额:
    $10.93万
  • 财政年份:
    2020
  • 负责人:
    Amsden, Brian
  • 依托单位:
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