Discrete dynamic complexes and phase-separated states of disordered proteins in neurobiology
Discrete dynamic complexes and phase-separated states of disordered proteins in neurobiology
批准号:
334016
负责人:
Forman-Kay Julie D
金额:
$103.88万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2015
资助国家:
加拿大
项目状态:
已结题
起止时间:
2015-09-01 至 2022-09-01
中文摘要
蛋白质是执行大多数生物功能的分子机器。一些蛋白质具有稳定的结构,但其他蛋白质,称为内在无序蛋白质(IDP),具有高度灵活性。紊乱在大脑蛋白质中非常丰富,特别是那些
英文摘要
Proteins are the molecular machines that perform most biological functions. Some proteins have stable structure but others, called intrinsically disordered proteins (IDPs), are highly flexible. Disorder is very abundant in brain proteins, particularly tho
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