Materials properties and biomechanics of stemmed implant devices

骨组织与生物医学植入装置（例如牙科植入物）的整合是一个复杂的过程。 这种现象取决于植入物的材料和机械性能。制造业 植入设备的成本直接转化为患者的高成本，新技术，如添加剂， 制造业可能为加拿大公司提供一种降低植入物生产成本的途径 装置.快速成型，如3D打印，正在迅速成为一种可行的增材制造工艺 能够生产复杂形状而不浪费原材料。在这个项目中，一种新的3D打印钛 由Stemmed Implant Technologies，Inc.公司生产的牙科植入装置。(SIT)将 研究了用于生产设备的材料和颗粒尺寸的选择对设备的性能有很大影响。 器械的机械性能以及对骨如何与其材料整合的最终影响 最终用途该公司在选择合适的材料和评估其影响方面面临挑战 在设备的设计上投入生产。本项目旨在确定材料的影响 选择，如原料化学和粒度，对整个反应器中机械力的分布的影响。 植入物系统，以建议最合适的原材料和最终产品的几何形状。作为材料 作为牙科和骨科植入材料领域的专家，在我的指导下，本研究将评估 材料选择对最终产品性能的影响，并提出改进设计和 生产过程，以生产在植入场景中适当分布负载的最终产品，以及 了解材料如何影响生物相容性。高分辨率成像技术，包括 透射电子显微镜（TEM）和定制的X射线显微计算机断层扫描（micro-CT） 将使用原位加载系统来研究这些装置。将这些新的植入物几何形状， 通过增材制造以低成本更快地推向市场，代表了医疗行业独特的经济机会。 这将为SIT等加拿大公司提供医疗器械行业的支持，并将转化为对加拿大人的直接健康益处。

The integration of bone tissue with biomedical implant devices, such as dental implants, is a complex phenomenon that is dependent on the materials and mechanical properties of the implant. As manufacturing costs of implant devices translate directly to high costs for patients, new technologies such as additive manufacturing may provide an avenue for Canadian companies to decrease the production cost of implant devices. Rapid prototyping, such as 3D printing, is quickly becoming a viable additive manufacturing process capable of producing complex shapes without wasting raw materials. In this project, a new 3D printed titanium dental implant device produced by the company Stemmed Implant Technologies, Inc. (SIT) will be investigated. The choice of material and particulate size used to produce the devices has a huge effect on the mechanical properties of the device and an ultimate effect on how bone will integrate with the material in its end use. The company is faced with a challenge in selecting appropriate materials, and evaluating their impact on the design of the device going to production. This project aims to identify the influence of materials selection, such as feedstock chemistry and particle size, on the distribution of mechanical forces throughout the implant system to advise on the most appropriate raw material and final product geometry. As a materials expert in the field of dental and orthopaedic implant materials, under my guidance this study will assess the influence of materials selection on the final product properties, and suggest improvements to the design and production process to produce a final product that distributes loads appropriately in an implant scenario, and understand how the material influences biocompatibility. High resolution imaging techniques including transmission electron microscopy (TEM) and a customized X-ray micro-computed tomography (micro-CT) in-situ loading system will be used to investigate the devices. Bringing these new implant geometries, produced at low cost via additive manufacturing, to market faster represent a unique economic opportunity in the medical device industry for Canadian companies such as SIT, and will translate to direct health benefits to Canadians.