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Characterizing in vitro and in vivo effects of the negative elongation factor (NELF) complex on controlling proliferative and differentiation states of myoblasts

Characterizing in vitro and in vivo effects of the negative elongation factor (NELF) complex on controlling proliferative and differentiation states of myoblasts
表征负延伸因子 (NELF) 复合物对控制成肌细胞增殖和分化状态的体外和体内作用
批准号：
350151
负责人：
Robinson Daniel C
金额：
$1.27万
依托单位：
University of Ottawa
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2015
资助国家：
加拿大
项目状态：
已结题
起止时间：
2015-12-01 至 2016-12-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=350151&lang=en
关键词：
Cell Cultures Gene Expression Microscopy Mouse Models Muscle Repair And Regeneration Muscular Dystrophy Myogenesis Negative Elongation Factor (Nelf) Complex Satellite Cells Transcription Regulation

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中文摘要
翻译
肌肉干细胞（卫星细胞）位于肌肉组织中，当骨骼肌因运动、拉伸或疾病而受损时，可以修复和再生。患有肌肉退行性疾病的人，如肌肉萎缩症和肌肉减少症
英文摘要
Muscle stem cells (satellite cells) located in muscle tissue allow to repair and regenerate skeletal muscle when damaged by exercise, stretching or disease. Persons affected by muscular degenerative diseases such as muscular dystrophy and sarcopenia have
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Characterizing in vitro and in vivo effects of negative elongation factor (NELF) in myogenesis
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