Understanding innate immune responses of insect vectors to intracellular pathogens.
Understanding innate immune responses of insect vectors to intracellular pathogens.
批准号:
261940-2013
负责人:
Lowenberger, Carl
金额:
$4.23万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2016
资助国家:
加拿大
项目状态:
已结题
起止时间:
2016-01-01 至 2017-12-31
中文摘要
这项提案将解决埃及伊蚊与人类之间的分子相互作用,埃及伊蚊是登革热病毒(DENV)的昆虫媒介。具体地说,我们将研究蚊子用来消除DENV的免疫过程,以及病毒如何规避这些反应。最近的研究讨论了调节或决定蚊子体内DENV细胞内发育的分子和途径的作用,但这些研究中的大多数使用了对DENV敏感的实验室蚊子株。
英文摘要
This proposal will address the molecular interactions between Aedes aegypti, the insect vector of Dengue viruses (DENv) to humans. Specifically we will look at the immune immune processes used by mosquitoes to eliminate DENv, and how the viruses circumvent these responses. Recent studies have addressed the role of molecules and pathways that regulate or determine the intracellular development of DENv in mosquitoes, but the majority of these studies have used lab strains of mosquitoes that are susceptible to DENv.
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会议论文
Untangling the complex molecular interplay in vector-pathogen interactions using bioinformatics, gene silencing, and gene editing.
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批准号:RGPIN-2019-04259
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项目类别:Discovery Grants Program - Individual
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资助金额:$4.23万
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财政年份:2022
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负责人:Lowenberger, Carl
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依托单位:
Untangling the complex molecular interplay in vector-pathogen interactions using bioinformatics, gene silencing, and gene editing.
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批准号:RGPIN-2019-04259
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项目类别:Discovery Grants Program - Individual
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资助金额:$4.23万
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财政年份:2021
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负责人:Lowenberger, Carl
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依托单位:
Untangling the complex molecular interplay in vector-pathogen interactions using bioinformatics, gene silencing, and gene editing.
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批准号:RGPAS-2019-00010
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项目类别:Discovery Grants Program - Accelerator Supplements
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资助金额:$5.83万
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财政年份:2020
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负责人:Lowenberger, Carl
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依托单位:
Untangling the complex molecular interplay in vector-pathogen interactions using bioinformatics, gene silencing, and gene editing.
-
批准号:RGPIN-2019-04259
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$4.23万
-
财政年份:2020
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负责人:Lowenberger, Carl
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依托单位:
Untangling the complex molecular interplay in vector-pathogen interactions using bioinformatics, gene silencing, and gene editing.
-
批准号:RGPIN-2019-04259
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项目类别:Discovery Grants Program - Individual
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资助金额:$4.23万
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财政年份:2019
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负责人:Lowenberger, Carl
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依托单位:
Untangling the complex molecular interplay in vector-pathogen interactions using bioinformatics, gene silencing, and gene editing.
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批准号:RGPAS-2019-00010
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项目类别:Discovery Grants Program - Accelerator Supplements
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资助金额:$2.91万
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财政年份:2019
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负责人:Lowenberger, Carl
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依托单位:
Understanding innate immune responses of insect vectors to intracellular pathogens.
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批准号:261940-2013
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项目类别:Discovery Grants Program - Individual
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资助金额:$4.23万
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财政年份:2018
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负责人:Lowenberger, Carl
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依托单位:
Understanding innate immune responses of insect vectors to intracellular pathogens.
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批准号:261940-2013
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项目类别:Discovery Grants Program - Individual
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资助金额:$4.23万
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财政年份:2015
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负责人:Lowenberger, Carl
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依托单位:
Understanding innate immune responses of insect vectors to intracellular pathogens.
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批准号:261940-2013
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项目类别:Discovery Grants Program - Individual
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资助金额:$4.23万
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财政年份:2014
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负责人:Lowenberger, Carl
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依托单位:
Understanding innate immune responses of insect vectors to intracellular pathogens.
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批准号:261940-2013
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项目类别:Discovery Grants Program - Individual
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资助金额:$4.23万
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财政年份:2013
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负责人:Lowenberger, Carl
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依托单位:
Immune interactions between insects and parasites
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批准号:261940-2008
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.28万
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财政年份:2012
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负责人:Lowenberger, Carl
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依托单位:
Canada Research Chair in the Biology of Parasites and Disease Vectors
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批准号:1000203661-2006
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项目类别:Canada Research Chairs
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资助金额:$7.29万
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财政年份:2011
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负责人:Lowenberger, Carl
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依托单位:
Immune interactions between insects and parasites
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批准号:261940-2008
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.28万
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财政年份:2011
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负责人:Lowenberger, Carl
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依托单位:
Canada Research Chair in the Biology of Parasites and Disease Vectors
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批准号:1000203661-2006
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项目类别:Canada Research Chairs
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资助金额:$7.29万
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财政年份:2010
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负责人:Lowenberger, Carl
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依托单位:
Immune interactions between insects and parasites
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批准号:261940-2008
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.28万
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财政年份:2010
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负责人:Lowenberger, Carl
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依托单位:
Canada Research Chair in the Biology of Parasites and Disease Vectors
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批准号:1000203661-2006
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项目类别:Canada Research Chairs
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资助金额:$7.29万
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财政年份:2009
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负责人:Lowenberger, Carl
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依托单位:
Immune interactions between insects and parasites
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批准号:261940-2008
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.28万
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财政年份:2009
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负责人:Lowenberger, Carl
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依托单位:
Immune interactions between insects and parasites
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批准号:261940-2008
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.28万
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财政年份:2008
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负责人:Lowenberger, Carl
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依托单位:
Canada Research Chair in the Biology of Parasites and Disease Vectors
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批准号:1000203661-2006
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项目类别:Canada Research Chairs
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资助金额:$7.29万
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财政年份:2008
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负责人:Lowenberger, Carl
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依托单位:
Characterization of the innate immune response in Rhodnius prolixus
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批准号:261940-2003
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.91万
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财政年份:2007
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负责人:Lowenberger, Carl
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依托单位:
国内基金
海外基金
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