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Mitochondrial Rejuvenation and Aging: Mechanistic evaluation of endurance exercise training as a countermeasure for aging in polymerase gamma mutator mice

Mitochondrial Rejuvenation and Aging: Mechanistic evaluation of endurance exercise training as a countermeasure for aging in polymerase gamma mutator mice
线粒体复兴和衰老:聚合酶γ突变小鼠耐力运动训练作为衰老对策的机制评估
批准号:
179964
负责人:
Tarnopolsky Mark A
金额:
$24.72万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2009
资助国家:
加拿大
项目状态:
已结题
起止时间:
2009-03-01 至 2012-03-01

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中文摘要
翻译
在大规模的人类流行病学研究中,耐力运动与较低的死亡、癌症、功能衰退和心血管疾病的风险有关。人类这种多系统效应背后的根本机制(S)尚不清楚;然而,
英文摘要
Endurance exercise has been associated with lower risk of death, cancer, functional decline and cardiovascular disease in large human epidemiological studies. The fundamental mechanism(s) behind this multi-systemic effect in humans is not clear; however,
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会议论文
Enhancing skeletal muscle health to improve the quality life in females and males with myotonic dystrophy type 1
  • 批准号:
    453323
  • 项目类别:
    Operating Grants
  • 资助金额:
    $36.22万
  • 财政年份:
    2021
  • 负责人:
    Tarnopolsky Mark A
  • 依托单位:
Characterization of novel exersomes that mediate the systemic pro-metabolic effects of exercise in aging and neuromuscular disorders.
  • 批准号:
    313750
  • 项目类别:
    Operating Grants
  • 资助金额:
    $129.59万
  • 财政年份:
    2014
  • 负责人:
    Tarnopolsky Mark A
  • 依托单位:
Characterization of Novel Exerkines Mediating Pro-metabolic Effects of Endurance Exercise.
  • 批准号:
    307389
  • 项目类别:
    Operating Grants
  • 资助金额:
    $32.38万
  • 财政年份:
    2014
  • 负责人:
    Tarnopolsky Mark A
  • 依托单位:
Characterization of the Signaling Events Modulating Endurance Exercise-mediated PGC-1a Sub-cellular Localization in Skeletal Muscle.
  • 批准号:
    238431
  • 项目类别:
    Operating Grants
  • 资助金额:
    $24.37万
  • 财政年份:
    2011
  • 负责人:
    Tarnopolsky Mark A
  • 依托单位:
海外基金